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10 Best Pimple Creams - Holiday Sale

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Last Updated - 2025/12/14

Best Choice

01
Neutrogena

Neutrogena Stubborn Acne Drying Lotion 29 mL
Main highlights

The Neutrogena Stubborn Acne Drying Lotion is clinically proven to provide effective results. From a dermatologist-recommended brand, this spot treatment is packed with 10% sulfur, the maximum level of sulfur available over the counter.
The Neutrogena Stubborn Acne Drying Lotion contains 4% niacinamide to target dark spots and 10% sulfur to penetrate pores and help eliminate stubborn acne. This pimple reducing lotion is fragrance-free, paraben-free, phthalate-free, dye-free, and oil-free.
Neutrogena Stubborn Acne Drying Lotion can be used as part of your daily skincare routine. To use, apply as directed. Can be used overnight and then rinse away in the morning with warm water. For all-day acne treatment, pair with Stubborn Acne Blemish patches.
Dry up and clear pimples while reducing redness and discomfort with Neutrogena Stubborn Acne Drying Lotion. This pimple spot treatment helps to dry and clear up acne spots overnight. This product is available in a 29 mL bottle of acne lotion.
Clarify your skin while reducing redness and pimples with Neutrogena Stubborn Acne Drying Lotion. Designed for acne-prone skin, this treatment works to penetrate pores and help eliminate acne while helping target dark spots and post-acne marks.
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9.9

Exceptional

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02
La Roche-Posay

La Roche-Posay Acne Face Cream with Salicylic Acid & Niacinamide, Effaclar Duo+M Face Moisturizer for Oily, Acne-Prone Skin. Helps Clear Pimples, Remove Blackheads & Prevent Breakouts, 40ML

15% Off Free Shipping
Main highlights

Tinted Moisturizers Available: For additional coverage, try out one of our 3 Unifiant Tined Effaclar Duo+M Moisturizers. Available in 3 shades: Light, Medium, and Deep, suitable for skin phototypes I-VI.
Safe Product: Tested on sensitive skin, under dermatological control. Paraben free, oil free, hypoallergenic (allergy tested), non comedogenic (does not clog pores)
Ideal for Many Skin Types: Effaclar Duo+ M is recommended for multiple skin types: oily skin, combination skin, acne-prone skin, enlarged pores and sensitive skin
Dermatological Ingredients: Formulated with LHA, Salicylic Acid, Niacinamide, and Phycobioma, this moisturizer combats blemishes, reduces redness, and controls excess oil.
Acne Treatment: Acne Face Cream Moisturizing Treatment with Salicylic Acid, LHA & Niacinamide
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9.8

Exceptional

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Value for Money

03
Clean & Clear

Clean & Clear Persa-Gel 5 Oil-Free Acne Spot Treatment with Maximum Strength 5% Benzoyl Peroxide, Topical Pimple & Acne Medication for Face Acne, Fragrance-Free, 28g

21% Off Free Shipping

9.1 Simple to use

8.7 worth the money

8.0 Moisturizing
Main highlights

To use, clean the skin and apply a thin layer of spot treatment to affected areas one to three times a day as a part of your daily acne skincare routine.
This maximum strength* acne treatment is formulated free of parabens, phthalates, fragrance, oil and dyes. It features a vegan formula that is not tested on animals and is packaged in a recyclable carton. *Highest non-prescription strength available Suitable for acne-prone or oily skin, fragrance free Persa-Gel 5 helps clear acne and kills acne-causing bacteria.
The benzoyl peroxide spot treatment for acne penetrates deep down into pores where acne begins.
Fragrance free acne spot treatment contains 5% benzoyl peroxide acne medication that goes to work immediately to help fight pimples and blemishes.
28-gram tube of Clean & Clear Persa-Gel 5 Oil-Free Acne Spot Treatment with Maximum Strength* 5% Benzoyl Peroxide acne medication to help effectively treat pimples and kills acne causing bacteria.*Highest non-prescription strength available
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9.7

Exceptional

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04
CeraVe

CeraVe Acne Control Gel For Face, Pimple & Pores, With Salicylic Acid, 3 Essential Ceramides, Niacinamides. Developed with Dermatologists, Non-Comedogenic, Oil-Free, Fragrance-Free, 40ml

12% Off Free Shipping
Main highlights

Minimizes Pores & Gently Exfoliates: Combines salicylic acid (BHA) and AHA for gentle exfoliation, reducing the appearance of pores
Lightweight & Oil-Free Gel: This non-comedogenic gel absorbs quickly without leaving a greasy residue, making it ideal for daily use
Hydrates & Supports Skin Barrier: Formulated with three essential ceramides, niacinamide, and hyaluronic acid to maintain a healthy skin barrier and prevent dryness
Developed with Dermatologists: Expertly formulated to be gentle yet effective for acne-prone skin
Acne Control Gel Treatment with 2% Salicylic Acid : Developed with dermatologists to help clear acne pimples and minimize the apparence of pores, while maintaining the protective skin barrier
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9.4

Excellent

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05
OXY

Oxy Deep Pore Acne Vanishing Treatment - 5% Benzoyl Peroxide – Stubborn Acne Control - Helps Treat, and Prevent Breakouts – Allows Skin to Heal - Dermatologist Tested

15% Off Free Shipping

8.7 Simple to use

8.0 worth the money

8.0 Aroma
Main highlights

SUITABLE FOR ALL SKIN TYPES: Dermatologist tested, ensuring a safe and effective solution for your acne concerns.
SOOTHING INGREDIENTS: Contains SymCalmin to soothe skin, along with Portulaca Extract to calm and reduce redness.
RAPID PIMPLE TREATMENT: Helps treat acne pimples and accelerates skin healing.
ACNE BACTERIA ELIMINATION: Targets and eliminates acne-causing bacteria for clearer skin.
5% BENZOYL PEROXIDE: Formulated with 5% Benzoyl Peroxide for quick acne blemish healing and prevention.
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9.3

Excellent

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06
Neutrogena

Neutrogena Rapid Clear Stubborn Acne Spot Treatment Gel with Maximum Strength 5% Benzoyl Peroxide Acne Treatment Medication for Acne Prone Skin Care, 28g

33% Off Free Shipping

9.3 Simple to use

8.7 worth the money

8.4 Aroma
Main highlights

Use maximum strength gel as part of your acne-clearing skincare products routine up to 3x per day
Spot treatment for acne-prone skin helps clear up even your most stubborn acne breakouts
One 28-gram tube of Neutrogena Rapid Clear Maximum Strength Acne Spot Treatment Gel, Stubborn Acne
Gel contains 5% benzoyl peroxide, the non-prescription acne medicine dermatologists recommend most
Clinically proven to rapidly reduce the size & redness of stubborn acne pimples in just two hours
Clears up breakouts you have now while also helping to prevent future ones from forming
Acne-fighting gel actively fights breakouts for continuous improvement in skin's appearance
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9.1

Excellent

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07
Neutrogena

Neutrogena Rapid Clear Acne and Pimple Spot Treatment Gel with Salicylic Acid and Witch Hazel, 15 mL

10% Off Free Shipping
Main highlights

Works to clear breakouts fast and helps stop new ones from forming, even before they become visible. For best use, cover the entire affected area with a thin layer of spot treatment one to three times daily after cleansing.
The maximum-strength formula of this acne medicine is designed for acne-prone skin and is clinically proven to reduce pimple size, swelling, and redness in eight hours.
Our pimple spot treatment contains witch hazel, a natural ingredient known for its skin-soothing properties, as well as 2 salicylic acid acne medicine to penetrate pores and clear blemishes.
From the 1 dermatologist-recommended brand, this spot treatment gel features powerful Microclear Technology designed to boost delivery of acne medicine which helps clear congested pores deep at the source.
0.5-fluid ounce tube of Neutrogena Rapid Clear Acne Eliminating Spot Treatment Gel with Witch Hazel made with salicylic acid and witch hazel to visibly reduce breakouts and help prevent acne
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8.9

Very Good

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08
Clean & Clear

Clean & Clear Advantage Acne Spot Treatment With Salicylic Acid Acne Medication, 22 mL

21% Off Free Shipping

9.1 Simple to use

8.2 worth the money

8.0 Moisturizing
Main highlights

Works beautifully under make-up
Water resistant, oil-free and PABA-free
This water-light sunscreen provides UVA/UVB protection with SPF 60
Suitable for use during outdoor activities such as biking or hiking
From a Dermatologist Recommended Brand
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8.8

Very Good

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09
VICHY

Vichy Normaderm Anti-Acne Spot Treatment With 10% Sulfur, Glycolic Acid & Niacinamide Vitamin B3. Dries out pimples overnight, prevents acne blemishes. Fragrance-free, Dermatologists-recommended, 20ML

25% Off Free Shipping

8.4 Light weight

8.0 worth the money

8.0 Aroma
Main highlights

Vichy Normaderm Anti-Acne Spot Treatment With 10% Sulfur, Glycolic Acid & Niacinamide Vitamin B3.
Suitable for Very Dry, Dry, Normal, Oily, Acne Prone, Combination, Sensitive, and Mature Skin
How to Use: Cleanse skin thoroughly with NORMADERM ANTI-ACNE PURIFYING GEL CLEANSER, Apply acne spot treatment directly onto the pimples at night after application of NORMADERM ANTI-ACNE DOUBLE-ACTION LOTION. Avoid eyes.
Fragrance-free, Dermatologists-recommended
Dries out pimples overnight, prevents acne blemishes.
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8.7

Very Good

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10
Cetaphil

Cetaphil Gentle Salicylic Acid Acne Serum, For Sensitive, Acne-Prone Skin, With Salicylic Acid & Niacinamide, Treats, Prevents & Reduces Acne, Fragrance Free, Hypoallergenic, Dermatologist Recommended

15% Off Free Shipping
Main highlights

Salicylic Acid to Fight Acne and Prevent Future Breakouts - This hydrating, gel-serum combines acne-fighting salicylic acid with a unique blend of gentle, skin-soothing ingredients for visibly clearer and smoother skin
Moisturizing and Nourishing Formula - Contains Niacinamide (Vitamin B3), Zinc and Prebiotics to help replenish the skin's moisture barrier, reduce the appearance of enlarged pores and post-acne marks
Lightweight, Non-Drying Acne Serum – Cetaphil Gentle SA Serum has a lightweight yet hydrating formula, that is non-greasy and easily absorbs into the skin
Formulated Specifically for Sensitive Skin – Fragrance free, hypoallergenic and non-comedogenic, this acne treatment is designed to be gentle on sensitive skin while revealing more even, brighter-looking skin
Dermatologist Recommended - As a leading brand for sensitive skin, Cetaphil products are recognized by the Canadian Dermatology Association
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8.6

Very Good

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