10 Best peptide serums in Canada

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Last Updated - 2025/08/29

Best Choice

01
The Ordinary

The Ordinary Multi-Peptide + Copper Peptides 1% Serum (30ml/1oz)

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Main highlights

The Ordinary Multi-Peptide + Copper Peptides 1% (Formally Known as “Buffet” + Copper Peptides 1%)
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9.8

Exceptional

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02
TOSOWOONG

TOSOWOONG 9 Peptide Skin Booster Serum, Niacinamide & Hyaluronic Acid Facial Essence for All Skin Types, Korean Skincare, Paraben-Free, 150ml, 5.07 fl.oz.

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Main highlights

Skin Boosting Serum with 9 Peptides that support healthy-looking elasticity and glow. Enhance your routine with this multi-functional serum for well-balanced, radiant skin.
Mild Formula Light Texture: The formula is mild and gentle for all skin types. Gentle enough to be used daily.
How to Use: After cleansing, apply 2-3 pumps of the Serum on your face. Layer on your favorite moisturizer for additional hydration.
First Step of Skincare: This lightweight serum with a toner-like texture absorbs quickly into the skin, making it a great first step in your daily skincare routine. Its quick absorption allows for easy layering with other products.
Authentic TOSOWOONG: Leading the K-beauty trend, TOSOWOONG provides specialized skincare solutions crafted with high-quality ingredients to support healthy-looking skin.
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9.7

Exceptional

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Value for Money

03
Eva Naturals

Eva Naturals Peptide Serum for Face – Collagen Boosting Anti-Aging Facial Serum for Wrinkles, Fine Lines & Microneedling – Skin Firming, Smoothing & Hydrating Peptides Booster

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8.9 Aroma

8.7 Fashion

8.4 worth the money
Main highlights

SKIN FIRMING, SMOOTHING & HYDRATING: Infused with collagen-supporting peptides and nourishing plant extracts, this facial serum works to visibly lift and firm the skin while providing deep hydration for a supple, refreshed feel. Its fast-absorbing formula helps smooth uneven texture, improve elasticity, and promote a more radiant complexion. Perfect for daily use, it can help soften the look of sagging or tired skin, leaving you with a healthier, revitalized appearance.
REDUCES WRINKLES & FINE LINES: Specially formulated as an anti-aging face serum for women, this collagen peptide booster helps minimize the look of deep wrinkles, expression lines, and crow’s feet while improving skin texture and luminosity. The potent peptide blend works to support elasticity and moisture balance, helping your skin appear firmer, more hydrated, and youthful. Perfect for those seeking a non-invasive option to address visible signs of skin aging daily.
MICRONEEDLING & ROLLER COMPANION: This peptide serum is the perfect partner for at-home or professional microneedling, derma pen, and facial roller treatments. The lightweight, silky texture glides effortlessly across the skin, allowing devices to move smoothly while delivering targeted hydration and nutrients. Designed to help calm post-procedure skin and encourage renewal, it supports improved tone, texture, and resilience for enhanced overall results from your skincare routine.
GENTLE, NON-GREASY & LAYERABLE: This collagen peptide serum is lightweight, non-greasy, and suitable for most skin types, making it ideal for morning and nighttime routines. It layers seamlessly under makeup, moisturizer, or sunscreen without pilling, ensuring your skin stays hydrated, smooth, and comfortable all day. Designed for consistent use, it helps maintain long-term skin health by supporting firmness, softness, and a youthful glow through peptide-powered nourishment.
COLLAGEN-BOOSTING PEPTIDE FORMULA: This powerful peptide serum for face combines multiple skin-loving peptides with hydrating botanicals to help boost natural collagen production and visibly improve firmness, elasticity, and tone. Ideal for use with a derma roller, microneedling pen, or micro-needling stamp to enhance absorption and maximize results, it supports smoother, plumper, and more radiant skin over time while helping to reduce the visible signs of aging.
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9.6

Exceptional

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04
Q+A

Q+A Peptide Facial Serum. A powerful anti-ageing Peptide face serum to revitalise your skin. 30ml/1fl.oz

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Main highlights

Pure Peptide aids collagen synthesis for skin renewal ‍
Magnesium PCA energises your skin with its anti-fatigue properties ‍️
Hyaluronic Acid rejuvenates and hydrates to tackle fine lines
A peptide serum to combat signs of ageing for a youthful glow
99.4% Natural Formula Cruelty-Free Alcohol-Free Fragrance-Free Vegan-Friendly
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9.5

Excellent

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05
DH Nutrition

Vegan Triple Peptide Wrinkle Defence Serum. Formulated with 3 Clinically Proven Anti-Aging Peptides: Argireline, Matrixyl & Replexium. Made in Canada

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Main highlights

PROACTIVE ANTI-AGING SKIN CARE: Peptides are a key ingredient to maintain healthy looking skin & defend against the signs of ageing. Containing the powerful peptides Argireline, Matrixyl & Replexium for injection free, smoother, firmer looking skin.
PEPTIDES, THE KEY TO SMOOTHER FIRMER LOOKING SKIN: Triple Peptide wrinkle cream is designed for all skin types & is perfect for both women & men’s skin care routines. Gentle enough to use daily in the morning & evening, we provide our Wrinkle Defence Serum in a large size for complete coverage of facial lines around the eyes, nose, mouth, forehead & neck.
NOT YOUR ORDINARY SKIN PEPTIDE SERUM: Daily Health Nutrition’s 3-In-1 Peptide Serum is an advanced anti-wrinkle peptide complex designed to help smooth the appearance of facial lines around the eyes, nose, mouth & forehead.
FORMULATED WITH FORTIFYING VEGAN, PLANT-BASED ORGANIC EXTRACTS to help moisturize & boost the skin's resilience, firm & tone. A scientifically developed serum that will help maintain radiant looking skin & defend against the signs of aging.
ADVANCED FIRMING WRINKLE DEFENSE SYSTEM: Formulated with powerful peptides in a BONUS 60ml SIZE, to promote suppleness & target the major signs of ageing in a gentle moisturizing serum. A gentle serum that is a good choice for sensitive skin.
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9.4

Excellent

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06
medicube

medicube PDRN Pink Peptide Serum, Pink glow serum, Peptide, Niacinamide, Hydrating & Moisturizing & Firming, Uneven Skin Tone, Korean Skincare | 1.01 fl.oz. (1.01 fl.oz., Rose PDRN (Vegan))

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KOREAN GLASS GLOW SKIN: This pink glow serum targets dull skin and boosts elasticity, helping to prevent future breakouts while enhancing the skin's glow and resilience.
Fast-Absorbing & Lightweight – Non-greasy formula that absorbs quickly, perfect for all skin
Deep Hydration – Locks in moisture for a soft, plump, and dewy finish.
Brightening & Even Tone – Targets dark spots and hyperpigmentation for a smoother, glowing complexion.
Barrier Protection – Soothes irritation and shields skin from environmental stressors.
Anti-Aging & Firming – Diminishes fine lines and wrinkles while improving skin elasticity.
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9.3

Excellent

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07
Eva Naturals

Eva Naturals Matrixyl 3000 Serum – Multi-Peptide & Argireline Formula for Face – Collagen Face Tightening – Helps Smooth Fine Lines & Wrinkles – Hydrating, Firming & Anti-Aging Skin Booster, 2 Oz

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VITAMIN C GLOW-BOOSTING & ANTIOXIDANT SUPPORT – Featuring Sodium Ascorbyl Phosphate, a stable Vitamin C derivative, this serum helps visibly refresh the appearance of uneven skin tone while delivering antioxidant protection to defend against environmental stressors. Skin looks refreshed, luminous, and revitalized with regular use. The gentle yet potent formula is suitable for layering with other treatments, making it a versatile anti-aging and glow-boosting step in any routine.
MULTI-PEPTIDE FORMULA FOR VISIBLE RESULTS – Powered by Matrixyl 3000 (Palmitoyl Tripeptide-1 & Palmitoyl Tetrapeptide-7) and Argireline, this advanced serum helps support natural collagen for firmer-looking skin and improved elasticity. It smooths and softens the look of fine lines and wrinkles while revitalizing the complexion, leaving skin appearing more lifted, refreshed, and youthful over time with consistent AM and PM use as part of your daily skincare routine.
LIGHTWEIGHT, FAST-ABSORBING TEXTURE – Designed for daily AM and PM application, this non-greasy serum sinks in quickly, delivering targeted actives deep into the skin’s surface layers for optimal performance. Use under sunscreen, makeup, or night cream, it won’t pill or leave residue. Suitable for all skin types, including sensitive skin, it keeps skin feeling smooth, hydrated, and fresh while addressing multiple signs of aging for a more youthful, radiant look.
HYDRATION & PLUMPING WITH HYALURONIC ACID – Sodium Hyaluronate, Aloe Vera, and glycerin deliver intense, lasting hydration to help plump skin and improve suppleness. The formula helps relieve the feeling of tightness or dryness while keeping skin comfortable and radiant. Lightweight and fast-absorbing, it works beautifully under moisturizer or makeup, creating a smooth, hydrated base that enhances the look of healthy, dewy skin all day without greasy residue.
CLEAN, ETHICALLY FORMULATED & SUITABLE FOR ALL SKIN TYPES – Made with skin-loving ingredients and free from parabens and harsh additives, this serum is gentle yet powerful. Its multi-peptide, Vitamin C, and hyaluronic acid blend addresses multiple signs of aging in one step. Eva Naturals Matrixyl 3000 Serum is designed for men and women looking to maintain a youthful, revitalized complexion, it’s a must-have addition to any anti-aging, firming, or hydrating skincare routine.
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9.0

Excellent

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08
RAZUYEN

RAZUYEN Peptides Serum for Face, Anti Aging Serum with Collagen, Peptides and B5, Helps to Remove Fine Lines and Wrinkles, Hydrating Serum, (1.01 Fl.Oz, 30ml)

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Main highlights

Safety and Purity: It is free from parabens, phthalates, and mineral oils, making it suitable for all skin types, including sensitive skin. It is dermatologist-tested and safe for daily use
Lightweight Texture: This serum features a lightweight, non-greasy texture that absorbs quickly into the skin. It ensures effective delivery of active ingredients without leaving a heavy or sticky residue
Deep Hydration: With ingredients like Sodium Hyaluronate (Hyaluronic Acid) and Panthenol, this face serum provides deep hydration. It helps to maintain optimal moisture levels in the skin, resulting in a smooth and radiant appearance
Barrier Repair: The serum contains ingredients that work to strengthen the skin's natural barrier and improve its resilience. These ingredients help to support the skin's natural repair processes
Anti-Aging Benefits: This RAZUYEN Anti Aging Serum is formulated with advanced anti-aging ingredients that help to visibly reduce the appearance of fine lines and wrinkles, enhance skin elasticity, and promote a firmer, more youthful complexion
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8.9

Very Good

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09
The Ordinary

The Ordinary Multi-Peptide + HA Serum, 30ml

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Water-based serum
Targets early Signs of Aging, Dryness, Signs of Aging
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8.7

Very Good

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10
Mary&May

Mary&May 6 Peptide Complex Serum - Advanced Wrinkle Improvement with Firming and Lifting Effects - Korean Skincare - Fragrance Free, Hypoallergenic, Quick Absorbing, 1.01oz.
Main highlights

WRINKLE IMPROVEMENT AND SKIN FIRMING: Enhance your skincare routine with the 6 Peptide Complex Serum, specifically formulated to improve wrinkles and provide a significant firming and lifting effect. This serum harnesses the power of six synergistic peptides, making it an ideal choice for anti-aging and skin rejuvenation.
KEY INGREDIENTS: 6 PEPTIDES: Featuring a potent blend of six peptides, each selected for their unique ability to synergize and enhance skin elasticity and firmness. This serum delivers visible results by reducing the appearance of fine lines and wrinkles, promoting a smoother, more youthful complexion.
HYPOALLERGENIC AND NON-IRRITATING FORMULA: Formulated with EWG green grade ingredients, our serum is free from harmful additives such as parabens, ethanol, mineral oil, and synthetic fragrances, ensuring it is hypoallergenic, non-sticky, and suitable for all skin types, including sensitive skin.
HOW TO USE FOR BEST RESULTS: Apply a small amount to your face and neck after cleansing and toning. Gently massage in upward motions until fully absorbed. Use morning and night for optimal firming and anti-aging effects. Pair with a moisturizer to lock in hydration and further enhance skin's elasticity.
COMMITMENT TO CLEAN BEAUTY FROM KOREA: Proudly hailing from Korea, MARY & MAY embodies the essence of clean beauty with a conscience. Our products are not only vegan and cruelty-free but also made with all EWG green grade ingredients. We are dedicated to eco-friendly practices, utilizing 100% recycled paper and soybean oil ink for our packaging. This commitment reflects our deep respect for both skin health and environmental sustainability.
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8.6

Very Good

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