10 Best otc acne treatment in Canada

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Last Updated - 2026/04/02

Best Choice

01
Neutrogena

Neutrogena Stubborn Marks PM Treatment - Acne, Retinol Skin Care, Vitamin A - post-acne marks exfoliator - Fragrance Free, 29mL

9.9 worth the money

9.9 Simple to use

8.2 For Gentle skin
Main highlights

Visibly improves the look of post-acne marks while you sleep with retinol SA. The nightly treatment delivers improved clarity and a more even tone in just one week.
Visibly improves the look of post-acne marks while you sleep with retinol SA. Neutrogena Stubborn Marks PM Treatment delivers improved clarity and a more even tone in just one week.
The treatment is formulated with retinol SA, a stabilized, highly refined form of vitamin A to provide a visibly improved complexion. The treatment works to support the skin’s natural exfoliation process while you sleep.
Neutrogena Stubborn Marks PM Treatment works to support skin’s natural exfoliation process. This night-time exfoliation treatment can be used nightly on freshly cleansed skin to improve clarity.
Neutrogena Stubborn Marks PM Treatment helps improve the look of post-acne marks. Each product contains 29-millilitre pump bottle of night-time skin treatment.
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9.7

Exceptional

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02
Neutrogena

Neutrogena Stubborn Marks PM Treatment - Acne, Retinol Skin Care, Vitamin A - post-acne marks exfoliator - Fragrance Free, 29mL

12% Off

9.9 worth the money

9.9 Simple to use

8.2 For Gentle skin
Main highlights

Visibly improves the look of post-acne marks while you sleep with retinol SA. The nightly treatment delivers improved clarity and a more even tone in just one week.
Visibly improves the look of post-acne marks while you sleep with retinol SA. Neutrogena Stubborn Marks PM Treatment delivers improved clarity and a more even tone in just one week.
The treatment is formulated with retinol SA, a stabilized, highly refined form of vitamin A to provide a visibly improved complexion. The treatment works to support the skin’s natural exfoliation process while you sleep.
Neutrogena Stubborn Marks PM Treatment works to support skin’s natural exfoliation process. This night-time exfoliation treatment can be used nightly on freshly cleansed skin to improve clarity.
Neutrogena Stubborn Marks PM Treatment helps improve the look of post-acne marks. Each product contains 29-millilitre pump bottle of night-time skin treatment.
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9.4

Excellent

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03
Benzagel

Benzagel 5% Benzoyl Peroxide Acne Wash, 85 Milliliters
Main highlights

“Micronized” to effectively penetrate your skin and deliver it's active ingredient where the bacteria is hiding, deep in your pores
Pharmacist-Recommended: Benzagel is recognized as the top pharmacist recommended acne treatment brand in Canada in the Pharmacy Practice + Business 2023 Survey on OTC Counselling and Recommendations
Maximum strength 5% Benzoyl Peroxide: a proven ingredient that eliminates acne-causing bacteria, and unclogs pores by clearing away dead skin cells
Benzagel Acne Wash has been given the official Recommended Seal of Approval from the Acne and Rosacea Society of Canada (ARSC)
An effective topical treatment for both uncomplicated facial acne, and acne vulgaris
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9.3

Excellent

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04
Benzagel

Benzagel 5% Benzoyl Peroxide Acne Wash, 85 Milliliters
Main highlights

“Micronized” to effectively penetrate your skin and deliver it's active ingredient where the bacteria is hiding, deep in your pores
Pharmacist-Recommended: Benzagel is recognized as the top pharmacist recommended acne treatment brand in Canada in the Pharmacy Practice + Business 2023 Survey on OTC Counselling and Recommendations
Maximum strength 5% Benzoyl Peroxide: a proven ingredient that eliminates acne-causing bacteria, and unclogs pores by clearing away dead skin cells
Benzagel Acne Wash has been given the official Recommended Seal of Approval from the Acne and Rosacea Society of Canada (ARSC)
An effective topical treatment for both uncomplicated facial acne, and acne vulgaris
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9.2

Excellent

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Value for Money

05
Neutrogena

Neutrogena Rapid Clear Stubborn Acne Spot Treatment Gel with Maximum Strength 5% Benzoyl Peroxide Acne Treatment Medication for Acne Prone Skin Care, 28g

26% Off

9.3 Simple to use

8.7 worth the money

8.4 Aroma
Main highlights

Use maximum strength gel as part of your acne-clearing skincare products routine up to 3x per day
Spot treatment for acne-prone skin helps clear up even your most stubborn acne breakouts
One 28-gram tube of Neutrogena Rapid Clear Maximum Strength Acne Spot Treatment Gel, Stubborn Acne
Gel contains 5% benzoyl peroxide, the non-prescription acne medicine dermatologists recommend most
Clinically proven to rapidly reduce the size & redness of stubborn acne pimples in just two hours
Clears up breakouts you have now while also helping to prevent future ones from forming
Acne-fighting gel actively fights breakouts for continuous improvement in skin's appearance
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9.0

Excellent

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06
Neutrogena

Neutrogena Rapid Clear Stubborn Acne Spot Treatment Gel with Maximum Strength 5% Benzoyl Peroxide Acne Treatment Medication for Acne Prone Skin Care, 28g

30% Off

9.3 Simple to use

8.7 worth the money

8.4 Aroma
Main highlights

Use maximum strength gel as part of your acne-clearing skincare products routine up to 3x per day
Spot treatment for acne-prone skin helps clear up even your most stubborn acne breakouts
One 28-gram tube of Neutrogena Rapid Clear Maximum Strength Acne Spot Treatment Gel, Stubborn Acne
Gel contains 5% benzoyl peroxide, the non-prescription acne medicine dermatologists recommend most
Clinically proven to rapidly reduce the size & redness of stubborn acne pimples in just two hours
Clears up breakouts you have now while also helping to prevent future ones from forming
Acne-fighting gel actively fights breakouts for continuous improvement in skin's appearance
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8.8

Very Good

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07
Clean & Clear

Clean & Clear Persa-Gel 5 Oil-Free Acne Spot Treatment with Maximum Strength 5% Benzoyl Peroxide, Topical Pimple & Acne Medication for Face Acne, Fragrance-Free, 28g

13% Off

9.1 Simple to use

8.7 worth the money

8.0 Moisturizing
Main highlights

To use, clean the skin and apply a thin layer of spot treatment to affected areas one to three times a day as a part of your daily acne skincare routine.
This maximum strength* acne treatment is formulated free of parabens, phthalates, fragrance, oil and dyes. It features a vegan formula that is not tested on animals and is packaged in a recyclable carton. *Highest non-prescription strength available Suitable for acne-prone or oily skin, fragrance free Persa-Gel 5 helps clear acne and kills acne-causing bacteria.
The benzoyl peroxide spot treatment for acne penetrates deep down into pores where acne begins.
Fragrance free acne spot treatment contains 5% benzoyl peroxide acne medication that goes to work immediately to help fight pimples and blemishes.
28-gram tube of Clean & Clear Persa-Gel 5 Oil-Free Acne Spot Treatment with Maximum Strength* 5% Benzoyl Peroxide acne medication to help effectively treat pimples and kills acne causing bacteria.*Highest non-prescription strength available
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8.7

Very Good

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08
Clean & Clear

Clean & Clear Persa-Gel 5 Oil-Free Acne Spot Treatment with Maximum Strength 5% Benzoyl Peroxide, Topical Pimple & Acne Medication for Face Acne, Fragrance-Free, 28g

17% Off

9.1 Simple to use

8.7 worth the money

8.0 Moisturizing
Main highlights

To use, clean the skin and apply a thin layer of spot treatment to affected areas one to three times a day as a part of your daily acne skincare routine.
This maximum strength* acne treatment is formulated free of parabens, phthalates, fragrance, oil and dyes. It features a vegan formula that is not tested on animals and is packaged in a recyclable carton. *Highest non-prescription strength available Suitable for acne-prone or oily skin, fragrance free Persa-Gel 5 helps clear acne and kills acne-causing bacteria.
The benzoyl peroxide spot treatment for acne penetrates deep down into pores where acne begins.
Fragrance free acne spot treatment contains 5% benzoyl peroxide acne medication that goes to work immediately to help fight pimples and blemishes.
28-gram tube of Clean & Clear Persa-Gel 5 Oil-Free Acne Spot Treatment with Maximum Strength* 5% Benzoyl Peroxide acne medication to help effectively treat pimples and kills acne causing bacteria.*Highest non-prescription strength available
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8.6

Very Good

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09
Clean & Clear

Clean & Clear Advantage Acne Spot Treatment With Salicylic Acid Acne Medication, 22 mL

19% Off

9.1 Simple to use

8.2 worth the money

8.0 Moisturizing
Main highlights

This acne spot treatment reduces visible signs of acne and pimples
For normal, oily, and combination skin
Contains 2-Percent salicylic acid acne medication
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8.5

Good

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10
Clean & Clear

Clean & Clear Advantage Acne Spot Treatment With Salicylic Acid Acne Medication, 22 mL

23% Off

9.1 Simple to use

8.2 worth the money

8.0 Moisturizing
Main highlights

This acne spot treatment reduces visible signs of acne and pimples
For normal, oily, and combination skin
Contains 2-Percent salicylic acid acne medication
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8.4

Good

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