10 Best oral flea medication for dogs in Canada

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Last Updated - 2026/09/09

Best Choice

01
K9 Advantix

K9 Advantix II Flea and Tick Treatment for Small Dogs weighing less than 4.5 kg (less than 10 lbs.)-6 doses

9.9 Simple to use

9.3 worth the money
Main highlights

Year-Round Tick Prevention: Dogs in Canada need protection whenever temperatures exceed 4°C. Protect your pet from ticks and the harmful diseases they spread like Lyme disease.
Trusted Efficacy: Controls fleas, ticks and lice on dogs within 24 hours of treatment and will continue to protect the dog from further infestations for up to 4 weeks.
Safe, Vet-Recommended Care: Get trusted flea & tick medication delivered right to your door without a prescription. This 6-pack provides a 6-month supply for Small Dogs under 4.5 kg (less than 10 lbs.).
Kills Through Contact: K9 Advantix II works on the surface of the skin. Unlike oral medication, fleas, ticks, and mosquitoes do not have to bite your dog to die. Also reduces biting by mosquitoes and stable flies.
Easy Application: Fragrance-free, topical spot-on drops are simple to apply, offering a stress-free, monthly routine for reliable flea & tick control.
Do Not Use on Cats Safe for dogs and puppies 8 weeks and older
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9.9

Exceptional

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Value for Money

02
K9 Advantix

K9 Advantix II - Flea/Tick Prevention - Vet Recommended - Medium Dog - 6-Pk

9.5 Simple to use

8.2 worth the money
Main highlights

Year-Round Tick Prevention: Dogs in Canada need protection whenever temperatures exceed 4°C. Protect your pet from ticks and the harmful diseases they spread like Lyme disease.
Trusted Efficacy: Controls fleas, ticks and lice on dogs within 24 hours of treatment and will continue to protect the dog from further infestations for up to 4 weeks.
Safe, Vet-Recommended Care: Get trusted flea & tick medication delivered right to your door without a prescription. This 6-pack provides a 6-month supply for Medium Dogs between 4.6 kg to 11 kg (10 lbs. to 24 lbs.).
Kills Through Contact: K9 Advantix II works on the surface of the skin. Unlike oral medication, fleas, ticks, and mosquitoes do not have to bite your dog to die. Also reduces biting by mosquitoes and stable flies.
Easy Application: Fragrance-free, topical spot-on drops are simple to apply, offering a stress-free, monthly routine for reliable flea & tick control.
Do Not Use on Cats Safe for dogs and puppies 8 weeks and older
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9.7

Exceptional

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03
Hartz

UltraGuard Pro Topical Flea & Tick Prevention for Dogs and Puppies - Over 28 kg, 3 Monthly Treatments
Main highlights

PREVENT RE-INFESTATION: Long-lasting monthly topical flea treatment that prevents re-infestations for 1 month with dual Insect Growth Regulators (IGRs) that protect your pet and their environment
FAST ACTING FULL BODY PROTECTION: The topical formula spreads across the skin using your dog's natural oil to quickly travel across the coat for full body protection from head to tail
EASY TO APPLY: Features the patented and easy-to-use Pro-Glide angled applicator with rounded edges for a softer more pleasant application experience suitable for all dogs
CONTROLS FLEAS & TICKS AND REDUCES MOSQUITO BITES: Controls fleas, flea eggs, flea larvae and ticks and prevents flea eggs from hatching and reduces biting by mosquitoes
6 MONTHLY FLEA & TICK TREATMENTS: Contains 3 single dose tubes (1 tube per monthly application) for non-stop protection for up to 3 months
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9.4

Excellent

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04
K9 Advantix

K9 Advantix II Flea and Tick Treatment for Medium Dogs weighing 4.6 kg to 11 kg (10 lbs. to 24 lbs.)-4 doses

9.7 Simple to use

8.7 worth the money

8.0 Taste
Main highlights

Safe for dogs and puppies 8 weeks and older
Kills ticks and fleas through contact with no biting required; also kills lice and mosquitoes
For use on dogs only; not safe for use on cats
Easy to apply topical treatment can be used monthly for year-round protection
Breaks the flea life cycle to treat and control flea infestations in the home
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9.1

Excellent

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05
TriOak

Flea and Tick Prevention for Dogs Chewable: Natural Soft Dog Treats, Oral Pet Treatment for Dogs Health & Immunity - Daily Supplement & Repellent Chews for Small, Large Dog, Puppy Flea & Tick Control
Main highlights

Supports Normal Immune Health: Beta-glucan, zinc, and B vitamins help support normal immune system function and everyday wellness during seasonal outdoor periods.
Supports Healthy Skin & Coat: Made with brewer’s yeast, B vitamins, zinc methionine, quercetin, and fish oil to help maintain healthy-looking skin, coat condition, and seasonal skin comfort.
Pumpkin & Prebiotic Support: Powdered pumpkin, pumpkin seed extract, inulin, and papaya extract help support digestive health, gut balance, and comfortable daily use.
Flea & Tick Season Support: Designed for your dog’s seasonal outdoor routine, these daily soft chews provide nutritional support during flea and tick season without the mess of topical applications.
Chicken & Coconut Flavor: Made with chicken liver meal, freeze-dried chicken powder, and chicken flavor for a tasty soft chew. Give once daily according to your dog’s weight as part of a seasonal wellness routine.
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9.0

Excellent

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06
TriOak

Flea and Tick Prevention for Dogs Chewable: Natural Soft Dog Treats, Oral Pet Treatment for Dogs Health & Immunity - Daily Supplement & Repellent Chews for Small, Large Dog, Puppy Flea & Tick Control
Main highlights

Supports Normal Immune Health: Beta-glucan, zinc, and B vitamins help support normal immune system function and everyday wellness during seasonal outdoor periods.
Supports Healthy Skin & Coat: Made with brewer’s yeast, B vitamins, zinc methionine, quercetin, and fish oil to help maintain healthy-looking skin, coat condition, and seasonal skin comfort.
Pumpkin & Prebiotic Support: Powdered pumpkin, pumpkin seed extract, inulin, and papaya extract help support digestive health, gut balance, and comfortable daily use.
Flea & Tick Season Support: Designed for your dog’s seasonal outdoor routine, these daily soft chews provide nutritional support during flea and tick season without the mess of topical applications.
Chicken & Coconut Flavor: Made with chicken liver meal, freeze-dried chicken powder, and chicken flavor for a tasty soft chew. Give once daily according to your dog’s weight as part of a seasonal wellness routine.
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8.9

Very Good

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07
ParaPet

Parapet K9 Praventa 360 for Large Dogs - 3 Tubes

9.1 worth the money

9.1 Simple to use
Main highlights

Safe and Effective Protection: Against adult fleas, flea larvae, flea eggs and ticks
Once-a-month topical flea and tick treatment - One application lasts 30 days
For use only on dogs and puppies weighing 11 kg-25 kg and over 12 weeks of age - Contains 3 tubes (3 ml). DO NOT USE ON CATS
Contains Imidacloprid, Permethrin and Pyriproxyfen: the same active ingredients found in the leading veterinary brand
Breaks the flea and tick lifecycle and prevents further infestation
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8.8

Very Good

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08
Advantage

Advantage II Flea Treatment for Medium Dogs weighing 4.6 kg to 11 kg (10 lbs. to 24 lbs.)-4 doses

9.9 Simple to use

8.4 worth the money
Main highlights

Safe for dogs and puppies 7 weeks and older
Kills fleas through contact – no biting required; Also treats lice
Easy-to-apply topical treatment can be used monthly for year-round protection
Contains four, monthly applications of flea protection for dogs weighing 11 kg to 25 kg
Breaks the flea life cycle to treat and control flea infestations in the home
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8.7

Very Good

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09
Advantage

Advantage II - Flea Protection - XL Dogs - Vet Recommended - 4-pack

10% Off

9.5 Simple to use

8.0 worth the money
Main highlights

Trusted Efficacy: Vet-recommended dog flea treatment kills fleas through contact, meaning they do not have to bite your pet to die. Kills fleas within 24 hours of treatment and protects against further flea infestations for up to 4 weeks.
Safe, Vet-Recommended Care: Get trusted flea defense delivered right to your door, no prescription required. This 4-pack provides a 4-month supply for Extra Large Dogs over 25 kg (over 55 lbs.).
Safe for dogs and puppies 7 weeks and older.
Easy Application: Fragrance-free, topical spot-on drops are simple to apply, offering a stress-free, monthly routine for reliable flea control.
Breaks Lifecycle: Comprehensive formula targets flea eggs, flea larvae, and adult fleas to halt existing infestations and provide effective flea prevention for your dog and home.
Active Defense: Protect your dog wherever they go. From daily walks and dog parks to backyard play, ensure your pet is shielded from fleas.
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8.5

Good

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10
ParaPet

Parapet K9 Praventa 360 for Extra Large Dogs - 3 Tubes

8.2 Simple to use

8.0 Taste

8.0 worth the money
Main highlights

Safe and Effective Protection: Against adult fleas, flea larvae, flea eggs and ticks
Once-a-month topical flea and tick treatment - One application lasts 30 days
For use only on dogs and puppies weighing over 25 kg and over 12 weeks of age - Contains 3 tubes (4.8 ml). DO NOT USE ON CATS
Contains Imidacloprid, Permethrin and Pyriproxyfen: the same active ingredients found in the leading veterinary brand
Breaks the flea and tick lifecycle and prevents further infestation
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8.4

Good

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