10 Best cystic acne medication in Canada

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Last Updated - 2025/07/01

Best Choice

01
BellamiLuxx

Butt Acne Clearing Treatment Cream: Body Acne Treatment Lotion for Folliculitis and Pimples on Back, Buttocks, Thighs With 2% Salicylic Acid & Tea Tree Oil - Butt Cream for Smooth Skin (1 Pack)

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Main highlights

Trusted by Users – High Repurchase Rate – 85%+ repurchase rate! A long-term solution for smoother, healthier skin.
Soothes & Strengthens Skin Barrier – Infused with Bisabolol (Chamomile) and Allantoin (Comfrey) to reduce irritation, calm redness, and promote skin recovery.
Purifies & Fights Acne-Causing Bacteria – Tea Tree Oil and Witch Hazel Extract work together to combat blemishes, control excess oil, and refine pores for a balanced complexion.
Hydration & Barrier Protection – Lactobacillus Ferment and Hyaluronic Acid deliver deep hydration, strengthen the skin’s microbiome, and support long-term skin health.
2% Salicylic Acid + Botanical Extracts – Science x Nature for Clearer Skin. Deeply cleanses pores, exfoliates dead skin, and prevents breakouts while reducing redness.
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9.8

Exceptional

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02
SMNutrition

DIM Supplement 200 mg | Estrogen Balance for Women & Men | Hormonal Acne, Hormone Balance, PMS, Bloating, Menopause, & Antioxidant Support | Clean Label Project Certified, Vegan, Soy-Free | 60 Pills

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9.9 simple to consume

9.1 worth the money

8.0 pain management
Main highlights

UNQUESTIONED QUALITY: DIM 200 is Clean Label Project Certified, Non-GMO Project Verified, Vegan.org Certified, HALAL Certified, Gluten Intolerance Group Certified, Soy-Free, Dairy-Free, Titanium Dioxide-Free, Silicon Dioxide Free, and formulated without the top 9 allergens. Active ingredients verified by third-party testing.
THE ELITE DIM SUPPLEMENT FOR A REASON: These are the hormone balance supplements women and men across the world know and trust. Our signature Diindolylmethane formula is Health Canada Licensed, 3rd-Party Tested, and manufactured in an FDA registered and inspected facility that is certified GMP compliant with NSF standards.
PAIRS WELL WITH CALCIUM D GLUCARATE: Calcium D-Glucarate by SMNutrition supports liver health and maximizes the hormone-balancing effects of DIM.* It is a great supplement to pair, especially if you’re just starting your new DIM regimen.
EVERYTHING IN ONE SMALL CAPSULE: Other DIM products require multiple capsules; not ours. Each capsule contains 200mg of DIM plus 2.5mg of BioPerine. Plus, every bottle contains a 2-month supply.
DIM, A REVOLUTION IN HORMONE BALANCE: DIM supplements for women and men support the metabolism of excess estrogen to help with menopause, bloating relief, acne, fitness, PMS relief and more.*
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9.7

Exceptional

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Value for Money

03
Neutrogena

Neutrogena Rapid Clear Stubborn Acne Spot Treatment Gel with Maximum Strength 5% Benzoyl Peroxide Acne Treatment Medication for Acne Prone Skin Care, 28g

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9.3 Simple to use

8.7 worth the money

8.4 Aroma
Main highlights

Use maximum strength gel as part of your acne-clearing skincare products routine up to 3x per day
Spot treatment for acne-prone skin helps clear up even your most stubborn acne breakouts
One 28-gram tube of Neutrogena Rapid Clear Maximum Strength Acne Spot Treatment Gel, Stubborn Acne
Gel contains 5% benzoyl peroxide, the non-prescription acne medicine dermatologists recommend most
Clinically proven to rapidly reduce the size & redness of stubborn acne pimples in just two hours
Clears up breakouts you have now while also helping to prevent future ones from forming
Acne-fighting gel actively fights breakouts for continuous improvement in skin's appearance
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9.5

Excellent

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04
Clean & Clear

Clean & Clear Advantage Acne Spot Treatment With Salicylic Acid Acne Medication, 22 mL

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9.1 Simple to use

8.2 worth the money

8.0 Moisturizing
Main highlights

Works beautifully under make-up
Water resistant, oil-free and PABA-free
This water-light sunscreen provides UVA/UVB protection with SPF 60
Suitable for use during outdoor activities such as biking or hiking
From a Dermatologist Recommended Brand
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9.4

Excellent

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05
Neutrogena

Neutrogena Rapid Clear Acne and Pimple Spot Treatment Gel with Salicylic Acid and Witch Hazel, 15 mL

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Main highlights

Works to clear breakouts fast and helps stop new ones from forming, even before they become visible. For best use, cover the entire affected area with a thin layer of spot treatment one to three times daily after cleansing.
The maximum-strength formula of this acne medicine is designed for acne-prone skin and is clinically proven to reduce pimple size, swelling, and redness in eight hours.
Our pimple spot treatment contains witch hazel, a natural ingredient known for its skin-soothing properties, as well as 2 salicylic acid acne medicine to penetrate pores and clear blemishes.
From the 1 dermatologist-recommended brand, this spot treatment gel features powerful Microclear Technology designed to boost delivery of acne medicine which helps clear congested pores deep at the source.
0.5-fluid ounce tube of Neutrogena Rapid Clear Acne Eliminating Spot Treatment Gel with Witch Hazel made with salicylic acid and witch hazel to visibly reduce breakouts and help prevent acne
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9.2

Excellent

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06
OXY

Oxy Deep Pore Acne Vanishing Treatment - 5% Benzoyl Peroxide – Stubborn Acne Control - Helps Treat, and Prevent Breakouts – Allows Skin to Heal - Dermatologist Tested

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8.7 Simple to use

8.0 worth the money

8.0 Aroma
Main highlights

SUITABLE FOR ALL SKIN TYPES: Dermatologist tested, ensuring a safe and effective solution for your acne concerns.
SOOTHING INGREDIENTS: Contains SymCalmin to soothe skin, along with Portulaca Extract to calm and reduce redness.
RAPID PIMPLE TREATMENT: Helps treat acne pimples and accelerates skin healing.
ACNE BACTERIA ELIMINATION: Targets and eliminates acne-causing bacteria for clearer skin.
5% BENZOYL PEROXIDE: Formulated with 5% Benzoyl Peroxide for quick acne blemish healing and prevention.
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9.1

Excellent

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07
Thursday Plantation

Thursday Plantation Tea Tree Acne Gel - Spot Solution for Breakout, Whiteheads, Blackheads, Pimples & Blemishes - Gentle for Teens & Adults - 10g

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Main highlights

TARGETED ACNE SOLUTION WITH TEA TREE OIL - Thursday Plantation’s acne gel is formulated with natural tea tree oil to target blemishes, purify pores, and reduce excess oil, helping to clear pimples, whiteheads, and blackheads.
SPOT APPLICATION FOR BLEMISH CONTROL - Lightweight and fast-absorbing, this targeted gel is perfect for direct application on problem areas like the forehead, chin, and cheeks, fitting effortlessly into any skincare routine for ongoing clarity.
GENTLE CARE FOR TEENS & ADULTS - Crafted for teens and adults, this smooth gel provides balanced care, helping manage breakouts without drying the skin. Its easy-to-apply texture integrates seamlessly into any skincare routine.
DAILY USE FOR CONSISTENTLY CLEARER SKIN - Add this gel into your morning and evening routine to help manage pimples, whiteheads, and blackheads. The easy-to-apply formula supports a balanced, refreshed complexion, enhancing your skincare regimen daily.
COMPACT AND PORTABLE TRAVEL SIZE - Packaged in a convenient 10g tube, this acne gel is perfect for on-the-go care. Easily fits into bags or purses for quick spot treatment wherever needed, providing clear-skin support anytime.
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8.9

Very Good

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08
Benzagel

Benzagel 5% Benzoyl Peroxide Acne Wash, 85 Milliliters

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Main highlights

“Micronized” to effectively penetrate your skin and deliver it's active ingredient where the bacteria is hiding, deep in your pores
Pharmacist-Recommended: Benzagel is recognized as the top pharmacist recommended acne treatment brand in Canada in the Pharmacy Practice + Business 2023 Survey on OTC Counselling and Recommendations
Maximum strength 5% Benzoyl Peroxide: a proven ingredient that eliminates acne-causing bacteria, and unclogs pores by clearing away dead skin cells
Benzagel Acne Wash has been given the official Recommended Seal of Approval from the Acne and Rosacea Society of Canada (ARSC)
An effective topical treatment for both uncomplicated facial acne, and acne vulgaris
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8.8

Very Good

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09
Panoxyl

PanOxyl Creamy Acne Wash - 4% Benzoyl Peroxide

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Main highlights

PH BALANCED: Contains 3 humectants and 4 emollients to combat dryness
DAILY CLEANSER: Gentle enough for everyday use
CLINICALLY PROVEN – Contains benzoyl peroxide which is a proven first line defense treatment for clear skin
BREAKS THE ACNE CYCLE: Cleans and unclogs pores to clear, treat and prevent acne
BECAUSE IT WORKS: Kills acne-causing bacteria
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8.7

Very Good

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10
Cetaphil

Cetaphil Gentle Salicylic Acid Acne Serum, For Sensitive, Acne-Prone Skin, With Salicylic Acid & Niacinamide, Treats, Prevents & Reduces Acne, Fragrance Free, Hypoallergenic, Dermatologist Recommended

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Main highlights

Salicylic Acid to Fight Acne and Prevent Future Breakouts - This hydrating, gel-serum combines acne-fighting salicylic acid with a unique blend of gentle, skin-soothing ingredients for visibly clearer and smoother skin
Moisturizing and Nourishing Formula - Contains Niacinamide (Vitamin B3), Zinc and Prebiotics to help replenish the skin's moisture barrier, reduce the appearance of enlarged pores and post-acne marks
Lightweight, Non-Drying Acne Serum – Cetaphil Gentle SA Serum has a lightweight yet hydrating formula, that is non-greasy and easily absorbs into the skin
Formulated Specifically for Sensitive Skin – Fragrance free, hypoallergenic and non-comedogenic, this acne treatment is designed to be gentle on sensitive skin while revealing more even, brighter-looking skin
Dermatologist Recommended - As a leading brand for sensitive skin, Cetaphil products are recognized by the Canadian Dermatology Association
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8.6

Very Good

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