10 Best cystic acne medication in Canada

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Last Updated - 2026/07/02

Best Choice

01
SMNutrition

DIM Supplement 200 mg | Estrogen Balance for Women & Men | Hormonal Acne, Hormone Balance, PMS, Bloating, Antioxidant & Menopause Supplements for Women | Canadian Made, Vegan Diindolylmethane | 60 Ct

9.9 simple to consume

9.1 worth the money

8.0 pain management
Main highlights

UNQUESTIONED QUALITY: DIM 200 is proudly Made in Canada and Health Canada Licensed. It is Third-Party Tested, Soy-Free, Dairy-Free, Titanium Dioxide-Free, Silicon Dioxide Free, and formulated without the top 9 allergens.
THE ELITE DIM SUPPLEMENT FOR A REASON: These are the hormone balance supplements women and men across the world know and trust. Our signature Diindolylmethane formula provides hormone support at every stage of life, ensuring that your nutrition is rounded out with the estrogen balance support you need.
PAIRS WELL WITH CALCIUM D GLUCARATE: Calcium D-Glucarate by SMNutrition supports liver health and maximizes the hormone-balancing effects of DIM.* CDG is a great supplement to pair, especially if you’re including DIM as part of your perimenopause supplements for women, or menopause supplements for women routine.
HORMONE HARMONY IN ONE SMALL CAPSULE: Other DIM products require multiple capsules; not ours. Each capsule contains 200mg of DIM plus 2.5mg of BioPerine. Plus, every bottle contains a 2-month supply.
DIM, A REVOLUTION IN HORMONE BALANCE: DIM supplements for women and men support the metabolism of excess estrogen to help with menopause, bloating relief, acne, fitness, PMS relief and more.
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9.9

Exceptional

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02
Produco

[BIOLEE] ACNEPRIS Acne Pimple Blemish Spot Serum Care Pen | Pine Pollen Roll-On Spot Care Pen 10 mL (0.34 fl oz) Non-Comedogenic Stainless-Steel Roller (Korea Beauty Cosmetic) 1ea
Main highlights

Precision Stainless-Steel Roller for Targeted Application – Non-porous steel roller applies formula directly to specific spots without affecting surrounding skin
Pine Pollen Extract as Key Ingredient – Enriched with pine pollen extract to support smoother looking, more balanced visible trouble-areas
Patented 4-Stage Trouble-Care System –Features pine pollen extract plus patented technologies to support balanced visible spots, combined with patented Anti-Sebum P for excess oil control, ProbioMETA G55 for visible surface renewal, and Derma-Clera for calming sensitive-looking zones.
Non-Comedogenic Formula for breakout-prone or oily zones – helping minimize the likelihood of pore clogging in visible spots and breakout-prone areas.
Lightweight, Non-Sticky Texture & Face-to-Body Use – Fast-absorbing, non-greasy formula layers under or over makeup; suitable for both face and body visible spots
BIOLEE Pine Pollen Roll-On Spot-Care Pen – A sleek roll-on pen-style applicator fits into your purse or pocket for discreet visible-spot attention anytime
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9.7

Exceptional

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Value for Money

03
Neutrogena

Neutrogena Rapid Clear Stubborn Acne Spot Treatment for Face with Maximum OTC Strength 5% Benzoyl Peroxide Medication – Reduces Severity & Size of Breakouts – 28g

9.3 Simple to use

8.7 worth the money

8.4 Aroma
Main highlights

Versatile Application - This Neutrogena stubborn acne spot treatment works on face, chest, and back acne treatment areas, letting you target breakouts wherever they appear for comprehensive coverage
Maximum OTC Strength - Features 5% benzoyl peroxide, the dermatologist-recommended acne control gel ingredient that clears existing breakouts while preventing new ones, improving your complexion over time
How to Use - Wash hands with non-medicated soap. Apply twice daily or as directed by doctor. Clean the skin thoroughly before applying this product. Cover the entire affected area with a thin layer one to three times daily.
Healthier-Looking Skin - This Neutrogena formula works to help clear stubborn acne and improve skin's appearance, delivering results that help you maintain healthier-looking skin effortlessly
Acne Spot Treatment - The Neutrogena Rapid Clear benzoyl peroxide acne spot treatment reduces size, severity, and number of pimples giving you visible relief when you need it most so you can face your day with confidence
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9.5

Excellent

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04
Clean & Clear

Clean & Clear Persa-Gel 5 Oil-Free Acne Spot Treatment with Maximum Strength 5% Benzoyl Peroxide, Topical Pimple & Acne Medication for Face Acne, Fragrance-Free, 28g

9.1 Simple to use

8.7 worth the money

8.0 Moisturizing
Main highlights

To use, clean the skin and apply a thin layer of spot treatment to affected areas one to three times a day as a part of your daily acne skincare routine.
This maximum strength* acne treatment is formulated free of parabens, phthalates, fragrance, oil and dyes. It features a vegan formula that is not tested on animals and is packaged in a recyclable carton. *Highest non-prescription strength available Suitable for acne-prone or oily skin, fragrance free Persa-Gel 5 helps clear acne and kills acne-causing bacteria.
The benzoyl peroxide spot treatment for acne penetrates deep down into pores where acne begins.
Fragrance free acne spot treatment contains 5% benzoyl peroxide acne medication that goes to work immediately to help fight pimples and blemishes.
28-gram tube of Clean & Clear Persa-Gel 5 Oil-Free Acne Spot Treatment with Maximum Strength* 5% Benzoyl Peroxide acne medication to help effectively treat pimples and kills acne causing bacteria.*Highest non-prescription strength available
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9.4

Excellent

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05
Clean & Clear

Clean & Clear Advantage Acne Spot Treatment With Salicylic Acid Acne Medication, 22 mL

9.1 Simple to use

8.2 worth the money

8.0 Moisturizing
Main highlights

This acne spot treatment reduces visible signs of acne and pimples
For normal, oily, and combination skin
Contains 2-Percent salicylic acid acne medication
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9.3

Excellent

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06
Benzagel

Benzagel Micronized 5% Benzoyl Peroxide Acne Gel for Acne Treatment, 60 Grams
Main highlights

Official Seal of Approval: Benzagel Acne Gel has been given the Recommended Seal of Approval from the Acne and Rosacea Society of Canada (ARSC)
Micronized Formula: Effectively penetrates your skin and delivers its active ingredient where the bacteria is hiding, deep in your pores
Maximum Strength 5% Benzoyl Peroxide: A proven ingredient that eliminates acne-causing bacteria and unclogs pores by clearing away dead skin cells
Effective Topical Treatment: Addresses both uncomplicated facial acne and acne vulgaris
Convenient Size: Comes in a 60-gram tube providing ample product for consistent acne treatment application
Canadian Manufacturing: Proudly manufactured in Canada with quality standards
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9.1

Excellent

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07
Benzagel

Benzagel 5% Benzoyl Peroxide Acne Wash for Acne Treatment, 85 Milliliters
Main highlights

Prevents New Breakouts: Helps prevent new pimples from forming while allowing the skin to heal naturally
Official Seal of Approval: Benzagel Acne Wash has been given the Recommended Seal of Approval from the Acne and Rosacea Society of Canada (ARSC)
Micronized Formula: Effectively penetrates your skin and delivers its active ingredient where the bacteria is hiding, deep in your pores
Maximum Strength 5% Benzoyl Peroxide: A proven ingredient that eliminates acne-causing bacteria, and unclogs pores by clearing away dead skin cells
Effective Topical Treatment: Addresses both uncomplicated facial acne and acne vulgaris
Convenient Size: Comes in an 85 milliliter bottle, providing ample product for regular use in your skincare routine
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9.0

Excellent

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08
OXY

Oxy Deep Pore Acne Vanishing Treatment - 5% Benzoyl Peroxide – Stubborn Acne Control - Helps Treat, and Prevent Breakouts – Allows Skin to Heal - Dermatologist Tested

25% Off

8.7 Simple to use

8.0 worth the money

8.0 Aroma
Main highlights

SUITABLE FOR ALL SKIN TYPES: Dermatologist tested, ensuring a safe and effective solution for your acne concerns.
SOOTHING INGREDIENTS: Contains SymCalmin to soothe skin, along with Portulaca Extract to calm and reduce redness.
RAPID PIMPLE TREATMENT: Helps treat acne pimples and accelerates skin healing.
ACNE BACTERIA ELIMINATION: Targets and eliminates acne-causing bacteria for clearer skin.
5% BENZOYL PEROXIDE: Formulated with 5% Benzoyl Peroxide for quick acne blemish healing and prevention.
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8.9

Very Good

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09
Neutrogena

Neutrogena Rapid Clear Acne and Pimple Spot Treatment Gel with Salicylic Acid and Witch Hazel, 15 mL
Main highlights

Works to clear breakouts fast and helps stop new ones from forming, even before they become visible. For best use, cover the entire affected area with a thin layer of spot treatment one to three times daily after cleansing.
The maximum-strength formula of this acne medicine is designed for acne-prone skin and is clinically proven to reduce pimple size, swelling, and redness in eight hours.
Our pimple spot treatment contains witch hazel, a natural ingredient known for its skin-soothing properties, as well as 2 salicylic acid acne medicine to penetrate pores and clear blemishes.
From the 1 dermatologist-recommended brand, this spot treatment gel features powerful Microclear Technology designed to boost delivery of acne medicine which helps clear congested pores deep at the source.
0.5-fluid ounce tube of Neutrogena Rapid Clear Acne Eliminating Spot Treatment Gel with Witch Hazel made with salicylic acid and witch hazel to visibly reduce breakouts and help prevent acne
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8.7

Very Good

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10
Thursday Plantation

Thursday Plantation Tea Tree Acne Gel - Spot Solution for Breakout, Whiteheads, Blackheads, Pimples & Blemishes - Gentle for Teens & Adults - 10g
Main highlights

TARGETED ACNE SOLUTION WITH TEA TREE OIL - Thursday Plantation’s acne gel is formulated with natural tea tree oil to target blemishes, purify pores, and reduce excess oil, helping to clear pimples, whiteheads, and blackheads.
SPOT APPLICATION FOR BLEMISH CONTROL - Lightweight and fast-absorbing, this targeted gel is perfect for direct application on problem areas like the forehead, chin, and cheeks, fitting effortlessly into any skincare routine for ongoing clarity.
GENTLE CARE FOR TEENS & ADULTS - Crafted for teens and adults, this smooth gel provides balanced care, helping manage breakouts without drying the skin. Its easy-to-apply texture integrates seamlessly into any skincare routine.
DAILY USE FOR CONSISTENTLY CLEARER SKIN - Add this gel into your morning and evening routine to help manage pimples, whiteheads, and blackheads. The easy-to-apply formula supports a balanced, refreshed complexion, enhancing your skincare regimen daily.
COMPACT AND PORTABLE TRAVEL SIZE - Packaged in a convenient 10g tube, this acne gel is perfect for on-the-go care. Easily fits into bags or purses for quick spot treatment wherever needed, providing clear-skin support anytime.
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8.5

Good

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