10 Best cystic acne medication in Canada

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Last Updated - 2025/09/01

Best Choice

01
SMNutrition

DIM Supplement 250 mg | Hormone Balance Supplements Women | Menopause & PMS Relief, Hormonal Acne Treatment, PCOS & Estrogen Metabolism Support Supplements | Made in Canada, Gluten-Free | 60 Ct.

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9.1 simple to consume

8.9 worth the money
Main highlights

THE ELITE DIM SUPPLEMENT FOR A REASON: These are the hormone balance supplements women across the world know and trust. Our signature Diindolylmethane formula is Made in Canada, Health Canada Licensed, 3rd-Party Tested, and manufactured in an FDA registered and inspected facility that is certified GMP compliant with NSF standards.
PAIRS WELL WITH CALCIUM D GLUCARATE: Calcium D-Glucarate by SMNutrition supports liver health and maximizes the hormone-balancing effects of DIM.* It is a great supplement to pair, especially if you’re just starting your new DIM regimen.
EVERYTHING IN ONE SMALL CAPSULE: Other DIM products require multiple capsules; not ours. Each capsule contains 250mg of DIM plus complementary ingredients, and every bottle contains a 2-month supply.
DIM OPTIMIZED FOR WOMEN: Diindolylmethane DIM supplements aid in hormone balance by supporting the body’s metabolism of excess estrogen.* DIM for women provides support for the typical symptoms of menopause, like hot flashes and hormonal acne.*
A MENOPAUSE MUST-HAVE: This complex pairs hormone-balancing DIM with Dong Quai to provide additional support for hot flashes and energy levels.* And with Vitamin D added for bone support, this is the DIM supplement women love, especially during menopause.*
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9.8

Exceptional

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02
VICHY

Vichy Normaderm Anti-Acne Spot Treatment With 10% Sulfur, Glycolic Acid & Niacinamide Vitamin B3. Dries out pimples overnight, prevents acne blemishes. Fragrance-free, Dermatologists-recommended, 20ML

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8.4 Light weight

8.0 worth the money

8.0 Aroma
Main highlights

Vichy Normaderm Anti-Acne Spot Treatment With 10% Sulfur, Glycolic Acid & Niacinamide Vitamin B3.
Suitable for Very Dry, Dry, Normal, Oily, Acne Prone, Combination, Sensitive, and Mature Skin
How to Use: Cleanse skin thoroughly with NORMADERM ANTI-ACNE PURIFYING GEL CLEANSER, Apply acne spot treatment directly onto the pimples at night after application of NORMADERM ANTI-ACNE DOUBLE-ACTION LOTION. Avoid eyes.
Fragrance-free, Dermatologists-recommended
Dries out pimples overnight, prevents acne blemishes.
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9.7

Exceptional

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Value for Money

03
Neutrogena

Neutrogena Rapid Clear Stubborn Acne Spot Treatment Gel with Maximum Strength 5% Benzoyl Peroxide Acne Treatment Medication for Acne Prone Skin Care, 28g

25% Off Free Shipping

9.3 Simple to use

8.7 worth the money

8.4 Aroma
Main highlights

Use maximum strength gel as part of your acne-clearing skincare products routine up to 3x per day
Spot treatment for acne-prone skin helps clear up even your most stubborn acne breakouts
One 28-gram tube of Neutrogena Rapid Clear Maximum Strength Acne Spot Treatment Gel, Stubborn Acne
Gel contains 5% benzoyl peroxide, the non-prescription acne medicine dermatologists recommend most
Clinically proven to rapidly reduce the size & redness of stubborn acne pimples in just two hours
Clears up breakouts you have now while also helping to prevent future ones from forming
Acne-fighting gel actively fights breakouts for continuous improvement in skin's appearance
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9.5

Excellent

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04
Clean & Clear

Clean & Clear Advantage Acne Spot Treatment With Salicylic Acid Acne Medication, 22 mL

13% Off Free Shipping

9.1 Simple to use

8.2 worth the money

8.0 Moisturizing
Main highlights

Works beautifully under make-up
Water resistant, oil-free and PABA-free
This water-light sunscreen provides UVA/UVB protection with SPF 60
Suitable for use during outdoor activities such as biking or hiking
From a Dermatologist Recommended Brand
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9.4

Excellent

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05
OXY

Oxy Deep Pore Acne Vanishing Treatment - 5% Benzoyl Peroxide – Stubborn Acne Control - Helps Treat, and Prevent Breakouts – Allows Skin to Heal - Dermatologist Tested

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8.7 Simple to use

8.0 worth the money

8.0 Aroma
Main highlights

SUITABLE FOR ALL SKIN TYPES: Dermatologist tested, ensuring a safe and effective solution for your acne concerns.
SOOTHING INGREDIENTS: Contains SymCalmin to soothe skin, along with Portulaca Extract to calm and reduce redness.
RAPID PIMPLE TREATMENT: Helps treat acne pimples and accelerates skin healing.
ACNE BACTERIA ELIMINATION: Targets and eliminates acne-causing bacteria for clearer skin.
5% BENZOYL PEROXIDE: Formulated with 5% Benzoyl Peroxide for quick acne blemish healing and prevention.
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9.3

Excellent

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06
Panoxyl

PanOxyl Creamy Acne Wash - 4% Benzoyl Peroxide

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Main highlights

PH BALANCED: Contains 3 humectants and 4 emollients to combat dryness
DAILY CLEANSER: Gentle enough for everyday use
CLINICALLY PROVEN – Contains benzoyl peroxide which is a proven first line defense treatment for clear skin
BREAKS THE ACNE CYCLE: Cleans and unclogs pores to clear, treat and prevent acne
BECAUSE IT WORKS: Kills acne-causing bacteria
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9.2

Excellent

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07
SMNutrition

DIM Supplement 200 mg | Estrogen Balance for Women & Men | Hormonal Acne, Hormone Balance, PMS, Bloating, Menopause, & Antioxidant Support | Canadian Made, Vegan, Soy-Free Diindolylmethane | 60 Ct

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9.9 simple to consume

9.1 worth the money

8.0 pain management
Main highlights

UNQUESTIONED QUALITY: DIM 200 is proudly Made in Canada and Health Canada Licensed. It is Third-Party Tested, Soy-Free, Dairy-Free, Titanium Dioxide-Free, Silicon Dioxide Free, and formulated without the top 9 allergens.
THE ELITE DIM SUPPLEMENT FOR A REASON: These are the hormone balance supplements women and men across the world know and trust. Our signature Diindolylmethane formula provides must-have support at every stage of life, ensuring that your nutrition is rounded out with the estrogen balance support you need.
PAIRS WELL WITH CALCIUM D GLUCARATE: Calcium D-Glucarate by SMNutrition supports liver health and maximizes the hormone-balancing effects of DIM.* It is a great supplement to pair, especially if you’re just starting your new DIM regimen.
EVERYTHING IN ONE SMALL CAPSULE: Other DIM products require multiple capsules; not ours. Each capsule contains 200mg of DIM plus 2.5mg of BioPerine. Plus, every bottle contains a 2-month supply.
DIM, A REVOLUTION IN HORMONE BALANCE: DIM supplements for women and men support the metabolism of excess estrogen to help with menopause, bloating relief, acne, fitness, PMS relief and more.*
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9.0

Excellent

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08
Benzagel

Benzagel 5% Benzoyl Peroxide Acne Wash, 85 Milliliters

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Main highlights

“Micronized” to effectively penetrate your skin and deliver it's active ingredient where the bacteria is hiding, deep in your pores
Pharmacist-Recommended: Benzagel is recognized as the top pharmacist recommended acne treatment brand in Canada in the Pharmacy Practice + Business 2023 Survey on OTC Counselling and Recommendations
Maximum strength 5% Benzoyl Peroxide: a proven ingredient that eliminates acne-causing bacteria, and unclogs pores by clearing away dead skin cells
Benzagel Acne Wash has been given the official Recommended Seal of Approval from the Acne and Rosacea Society of Canada (ARSC)
An effective topical treatment for both uncomplicated facial acne, and acne vulgaris
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8.9

Very Good

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09
Thursday Plantation

Thursday Plantation Tea Tree Acne Gel - Spot Solution for Breakout, Whiteheads, Blackheads, Pimples & Blemishes - Gentle for Teens & Adults - 10g

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Main highlights

TARGETED ACNE SOLUTION WITH TEA TREE OIL - Thursday Plantation’s acne gel is formulated with natural tea tree oil to target blemishes, purify pores, and reduce excess oil, helping to clear pimples, whiteheads, and blackheads.
SPOT APPLICATION FOR BLEMISH CONTROL - Lightweight and fast-absorbing, this targeted gel is perfect for direct application on problem areas like the forehead, chin, and cheeks, fitting effortlessly into any skincare routine for ongoing clarity.
GENTLE CARE FOR TEENS & ADULTS - Crafted for teens and adults, this smooth gel provides balanced care, helping manage breakouts without drying the skin. Its easy-to-apply texture integrates seamlessly into any skincare routine.
DAILY USE FOR CONSISTENTLY CLEARER SKIN - Add this gel into your morning and evening routine to help manage pimples, whiteheads, and blackheads. The easy-to-apply formula supports a balanced, refreshed complexion, enhancing your skincare regimen daily.
COMPACT AND PORTABLE TRAVEL SIZE - Packaged in a convenient 10g tube, this acne gel is perfect for on-the-go care. Easily fits into bags or purses for quick spot treatment wherever needed, providing clear-skin support anytime.
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8.7

Very Good

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10
Benzagel

Benzagel Spot-On 2.5% Benzoyl Peroxide Gel, 15mL - Made in Canada

28% Off Free Shipping
Main highlights

Where to use it: "Spot-On" Acne Gel can be carried in pocket or purse, so you can use it at school on a date at the dance—wherever you are when pimple spots appear
The "Spot On" applicator features a NEW pinpoint silicone tip that's soft on skin, hygienic, accurate
Spot On Acne Gel is specifically formulated for day to day on the go use, with ingredients selected for their gentleness and compatibility with most skin types
Pharmacist-Recommended: Benzagel is recognized as the top pharmacist recommended acne treatment brand in Canada in the Pharmacy Practice + Business 2023 Survey on OTC Counselling and Recommendations
Made in Canada
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8.6

Very Good

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