10 Best anxiety supplements for dogs in Canada

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Last Updated - 2026/07/01

Best Choice

01
Pro Plan Veterinary Diets

Purina Pro Plan Veterinary Supplements Calming Care Powdered Dog Calming Probiotic - 1 g Sachet (30 Pack)
Main highlights

Probiotic strain shown to help dogs maintain calm behaviour
Helps promote a positive emotional state in dogs
Helps dogs maintain positive cardiac activity during stressful events
Helps dogs cope with external stressors like separation, unfamiliar visitors, novel sounds, or changes in routine and location
Excellent Palatability
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9.8

Exceptional

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Value for Money

02
Zesty Paws

Zesty Paws Calming Chews for Dogs - Helps Promote Relaxation & Calmness - Dog Calming Chews with Suntheanine, Ashwagandha & Chamomile for Thunderstorms, Fireworks & Travel - Turkey Flavour - 90 Count

8.9 Taste

8.2 worth the money

8.0 pain management
Main highlights

Support for Stressful Events - dog vitamins with calming support include Passion Flower to help relieve nervousness and/or restlessness.
Premium Calming Support - dog chew for calming support in animals experiencing external stressors and during stressful events such as storms and traveling.
Plus Ashwagandha - dog calming products also includes Ashwagandha to help maintain calmness for any small, medium, or large dog.
Featuring Suntheanine - dog calming treats contains Suntheanine, a clinically studied and super premium form of L-Theanine that helps to temporarily promote relaxation for your pup.
Delicious Flavour Dogs Love - Your dog will love the tasty turkey flavour while getting pawsome calming support from Chamomile, Valerian Root, Hemp Seed Powder, and L-Tryptophan.
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9.7

Exceptional

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03
Bark&Spark

Advanced Calming Hemp Treats for Dogs - Hemp Oil + Melatonin - Anxiety Relief - Separation Aid - Stress Relief During Fireworks, Storms, Thunder - Aggressive Behavior, Barking - 120 Soft Chews

9.1 Aroma

9.1 Taste

8.7 worth the money
Main highlights

Moderate Anxiety and Stress - these calming treats help reduce symptoms of anxiety or stress such as growling, barking, scratching, chewing, licking, uncontrolled urination etc. Anti-anxiety treats can be used to relax your pet during separation, car rides, vet visits, thunders, firework etc
Moderate Aggressive or Hyperactive Behavior - dog's aggressive behaviour like barking or growling, or hyperactive strolling or running is often caused by unfamiliar surrounding or stressful events, so our calming treats are formulated to keep your buddy calm and composed even in the most stressful moments.
Is Your Dog a Picky Eater? We stick to simple formulas rich in natural bacon flavor, that could tempt a fussy eater. No hassle with pills, powder, tablets or capsules
Bark&Spark Commitment - we are keen to give best treatment to our furry customers and we take no compromise when it comes to product quality. Our calming treats are made in the USA, with human grade ingredients
Advanced Dog Calming with Melatonin - formulated with known effective calming ingredients, like hemp oil, valerian root, chamomile and melatonin, this treats are effective but more importantly safe and healthy supplements. No chemical relaxants or sedatives are used. Suitable for hyper dogs of all breeds, sizes. Safe to use for puppies as well.
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9.6

Exceptional

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04
CANNANDA

CB2 Hemp Oil for Dogs [225,000mg / 240mL / Organic] - Natural Hip and Joint Supplement for Dogs - Calming Anxiety Relief - Extra Strength for Pain, Inflammation, Arthritis, Stress, Aggression

8.9 worth the money

8.9 Comfort

8.7 pain management
Main highlights

🇨🇦 MADE IN CANADA 🇨🇦: CB2 is a Canadian brand. All our CB2 products are made in Canada from Canadian grown organic hemp. Join over 1 Million happy, healthy dogs across North America who trust CB2. Click “Add to Cart” or “Subscribe and Save” for great savings. YOUR BEST BUDDY DESERVES THE POWER OF CB2!
VETERINARIAN RECOMMENDED: 100X the strength and effectiveness vs standard hemp oil or glucosamine. Supercharged with 1800mg of proprietary CB2 extract for maximum potency. Doctor formulated and recommended by vets across Canada. Powerful daily support for your dog’s comfort, energy, mobility, and overall wellness
QUALITY ASSURANCE CERTIFIED: Therapeutic Grade + Human Grade. Made with all natural ingredients and certified organic hemp oil rich in Omega 3. Non-GMO. Zero THC. No psychoactive effects. No drowsiness. No sedation. No known side effects. Appropriate for all dogs, all breeds, all sizes, and all ages. Registered with Health Canada as a VHP certified dog supplement.
PAIN & INFLAMMATION: Is your best friend slowing down because of joint pain or arthritis? Don’t let pain steal your dog’s best years. CB2 is the most effective hip and joint supplement for dogs, delivering powerful support for pain, stiffness, inflammation, and mobility issues. Excellent for arthritis, joint pain, hip dysplasia, aging, and injuries. Helps bring back comfort, flexibility, strength, and quality of life. Excellent for senior dogs and ideal for all ages
EXTRA LARGE 240mL BOTTLE: Bigger bottle. Better value. While many companies sell tiny 30mL or 60mL bottles, our extra large 240mL bottle gives you far more oil for long-term daily use. Outstanding value for dogs who need consistent daily support. More effective than glucosamine for dogs, fish oil for dogs, omega 3 for dogs, and salmon oil for dogs
ANXIETY & STRESS: It’s heartbreaking to watch your dog suffer from fear, anxiety, and stress. CB2 helps bring your dog back to a calm, relaxed, and emotionally balanced state. Powerful calming relief for dogs without sedation. Excellent for separation anxiety, travel, grooming, motion sickness, and tension caused by changes in your dog’s daily routine. Helps reduce aggression, excessive barking, hyperactivity, and nervous behavior
100% GUARANTEED: We are so confident in the premium quality of our CB2 products that we promise a full money-back guarantee on your FIRST bottle! If you are not 100% satisfied with your first bottle for any reason, we will issue you an immediate refund. No questions asked. No return required. Try it absolutely risk-free! We truly care about your dogs, and we value integrity and trust. IMPORTANT: Amazon does not allow returns of pet health products. To activate your satisfaction guarantee, follow the instructions and customer service contact provided on the paper insert included with every bottle
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9.5

Excellent

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05
Bark&Spark

Calming Hemp Treats for Dogs - Made in USA with Hemp Oil - Anxiety Relief - Separation Aid - Stress Relief During Fireworks, Storms, Thunder - Aggressive Behavior, Barking - 120 Soft Chews

8.0 Taste

8.0 worth the money

8.0 pain management
Main highlights

Natural Formula for All Breeds and Sizes - product formulated with known effective calming ingredients, like hemp oil, chamomile and passion flower extracts, this treats are effective but more importantly safe and healthy supplement. No chemical relaxants or sedatives are used in this formula. Suitable for hyper dogs of all breeds and sizes.
Moderate Aggressive or Hyperactive Behavior - dog's aggressive behaviour like barking or growling, or hyperactive stolling or running is often caused by unfamiliar surrounding or stressful activity (like a visit to a veterinarian or car ride), and our calming treats can be used to keep your 4 paws friend calm and composed even in the most stressful moments.
Made in USA from Sustainably Sourced Ingredients - these calming hemp bites are made in the USA, with USA grown and processed ingredient. Treats contain absolutely NO sugar, dairy or cord.
Effective Calming Supplement - these calming treats help reduce symptoms of anxiety or stress such as growling, barking, scratching, chewing, licking, uncontrolled urination etc. Anti-anxiety treats are specially formulated to calm down your pet's anxiety, aggression during separation, car rides, thunders, firework etc
A Treat with Delicious Flavor - even the best supplement won't be any good if the dog won't eat it, so we added natural bacon flavoring to our products, so even a picky eater will love it.
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9.4

Excellent

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06
Nutrience

Nutrience Care® Calming Dog Supplement, 100 Soft Chews, 400 g
Main highlights

Veterinary approved
Reduces nervousness, tension, anxiety and stress
Promotes relaxation and supports a positive emotional state
Made in Canada
L-Tryptophan: aids in serotonin production, contributing to mood regulation and emotional stability
Ginger: helps ease nausea and motion sickness
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9.3

Excellent

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07
CANNANDA

CB2 Hemp Oil for Dogs [100 ML/Organic] Hip and Joint Supplement for Dogs - Extra Strength for Pain & Anxiety. Relieves Pain/Arthritis/Inflammation/Separation Anxiety/Stress/Made in Canada

8.9 worth the money

8.9 Comfort

8.7 pain management
Main highlights

🇨🇦 MADE IN CANADA 🇨🇦: CB2 is a Canadian brand. All our CB2 products are made in Canada from Canadian ingredients. Join over 1 Million happy, healthy dogs across North America who trust CB2. Click “Add to Cart” or “Subscribe & Save” for super savings. YOUR BEST BUDDY DESERVES THE ULTRA-CONCENTRATED POWER OF CB2!
VETERINARIAN RECOMMENDED: 100X the strength and effectiveness vs regular hemp oil. Contains a powerful 225,000mg of organic hemp oil + Omega 3 + CB2 extract for maximum potency. CAUTION: most companies sell tiny 30mL or 60mL bottles. Our larger 100mL bottle delivers excellent value and long-term benefits for your dog
STRONGER AND MORE EFFECTIVE THAN: fish oil for dogs / salmon oil for dogs / omega 3 for dogs / hemp treats / glucosamine for dogs. Unleash the power of CB2 for your dog's health and wellness. EXCELLENT RESULTS: Join over 1 Million happy and healthy dogs across North America who trust CB2!
QUALITY ASSURANCE CERTIFIED: Therapeutic Grade + Human Grade. Made with all natural, pure ingredients and certified organic hemp oil from Canadian-grown hemp. Non-GMO. Zero THC. No psychoactive effects. No drowsiness. No sedation. No known side effects. Appropriate for dogs of all breeds, sizes, and ages. Registered with Health Canada as a certified Veterinary Health Product (VHP). Made in Canada by a Canadian company
PAIN & INFLAMMATION: Is your best friend slowing down because of joint pain or arthritis? Don’t let them suffer any longer. CB2 Hip and Joint Supplement For Dogs is rich in Omega 3 and highly effective for pain, stiffness, and mobility issues. Excellent for arthritis, joint pain, hip dysplasia, aging, and injuries. Helps support joint lubrication, mobility, and flexibility. Stronger than glucosamine for dogs. Excellent for senior dogs and ideal for all breeds and ages
ANXIETY & STRESS: It's so hard to watch our best friends suffer from fear, anxiety, and stress. CB2 helps your dog maintain a calm and relaxed nature without sedation. Helps with separation anxiety, travel, motion sickness, and tension caused by changes in your dog’s daily routine. Significantly lowers stress levels and also helps reduce behavioral issues such as aggression, excessive barking, and hyperactivity
100% GUARANTEED: We are so confident in the premium quality of our CB2 products that we promise a full money-back guarantee on your FIRST bottle! If you are not 100% satisfied with your first bottle for any reason, we will issue you an immediate refund. No questions asked. No return required. Try it absolutely risk-free! We truly care about your dogs, and we value integrity and trust. IMPORTANT: Amazon does not allow returns of pet health products. To activate your satisfaction guarantee, follow the instructions and customer service contact provided on the paper insert included with every bottle
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9.1

Excellent

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08
true leaf

True Leaf Pet Calming Hemp Chews for Dogs 90g – Relaxing Formula with Hemp Seed Powder, L-Theanine & Chamomile – Supports Calm Behavior, Eases Stress & Anxiety Naturally – Made in Canada
Main highlights

Supports your dog’s health with a functional snack throughout the day.
Reignites your pet’s natural zest for life.
Omega-3 fatty acids from Hemp help support healthy brain activity and nerve function.
L-theatine is an amino acid found in Green Tea known to produce a calming effect.
Helps reduce stress.
Extracts of chamomile and lemon balm can help lower stress
Can help calm your pet.
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8.8

Very Good

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09
CANNANDA

CB2 Oil for Dogs - Advanced Hip and Joint Supplement for Dogs & Calming Anxiety Relief for Dogs. Ultra Concentrated Drops for Pain, Inflammation, Arthritis, Anxiety, Stress, Aggression. Made in Canada

8.9 pain management

8.2 worth the money

8.0 Taste
Main highlights

VETERINARIAN RECOMMENDED: 100X the strength and effectiveness vs hemp oil or glucosamine. Ultra concentrated: maximum potency in just a few drops per day. Doctor formulated and recommended by vets across Canada. Powerful daily support for your dog’s comfort, energy, mobility, and overall wellness
QUALITY ASSURANCE CERTIFIED: Therapeutic Grade + Human Grade. Made with advanced all natural phyto-botanical extracts for maximum potency. Non-GMO. Zero THC. No psychoactive effects. No drowsiness. No sedation. No side effects. Appropriate for all dogs, all breeds, all sizes, and all ages. Made in Canada in an FDA-regulated / GMP-certified facility
PAIN & INFLAMMATION: Is your best friend slowing down because of joint pain or arthritis? Don’t let pain steal your dog’s best years. CB2 is the most effective hip and joint supplement for dogs, delivering ultra-concentrated support for pain, stiffness, inflammation, and mobility issues. Powerful relief for arthritis, joint pain, hip dysplasia, joint stiffness, aging, and injuries. Helps bring back comfort, mobility, strength, and quality of life. Excellent for senior dogs and ideal for all ages
ANXIETY & STRESS: It’s heartbreaking to watch your dog suffer from fear, anxiety, and stress. CB2 helps bring your dog back to a calm, relaxed, and emotionally balanced state. Powerful calming relief for dogs without sedation. Excellent for separation anxiety, travel, grooming, motion sickness, and tension caused by changes in your dog’s daily routine. Helps reduce aggression, excessive barking, hyperactivity, and nervous behavior
100% GUARANTEED: We are so confident in the premium quality of our CB2 products that we promise a full money-back guarantee on your FIRST bottle! If you are not 100% satisfied with your first bottle for any reason, we will issue you an immediate refund. No questions asked. No return required. Try it absolutely risk-free! We truly care about your dogs, and we value integrity and trust. IMPORTANT: Amazon does not allow returns of pet health products. To activate your satisfaction guarantee, follow the instructions and customer service contact provided on the paper insert included with every bottle
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8.7

Very Good

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10
PET NATURALS

Pet Naturals of Vermont Calming for Dogs, Behavioral Support Supplement, Chicken Liver Flavor, 90 Bite-Sized Chews ,90 Count (Pack of 1)

8.0 Taste

8.0 worth the money

8.0 Comfort
Main highlights

age range description: All Stages
Tasty chicken Liver-flavored chews made without corn, wheat or artificial ingredients
Supports calm behavior with a powerful blend of ingredients including l-tryptophan, l-theanine, lemon balm and thiamine (vitamin B1).
Safe to double or triple dose during times of heightened stress. It can also be used daily or when needed.
Recommended for stressful situations like vet and grooming visits, car rides, thunderstorms and separation anxiety.
Behavior support supplement shown to have a calming effect on dogs that are stressed or anxious.
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8.5

Good

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