10 Best anxiety meds for dogs in Canada

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Last Updated - 2026/07/01

Best Choice

01
Pro Plan Veterinary Diets

Purina Pro Plan Veterinary Supplements Calming Care Powdered Dog Calming Probiotic - 1 g Sachet (30 Pack)
Main highlights

Probiotic strain shown to help dogs maintain calm behaviour
Helps promote a positive emotional state in dogs
Helps dogs maintain positive cardiac activity during stressful events
Helps dogs cope with external stressors like separation, unfamiliar visitors, novel sounds, or changes in routine and location
Excellent Palatability
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9.9

Exceptional

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Value for Money

02
Zesty Paws

Zesty Paws Calming Chews for Dogs - Helps Promote Relaxation & Calmness - Dog Calming Chews with Suntheanine, Ashwagandha & Chamomile for Thunderstorms, Fireworks & Travel - Turkey Flavour - 90 Count

8.9 Taste

8.2 worth the money

8.0 pain management
Main highlights

Support for Stressful Events - dog vitamins with calming support include Passion Flower to help relieve nervousness and/or restlessness.
Premium Calming Support - dog chew for calming support in animals experiencing external stressors and during stressful events such as storms and traveling.
Plus Ashwagandha - dog calming products also includes Ashwagandha to help maintain calmness for any small, medium, or large dog.
Featuring Suntheanine - dog calming treats contains Suntheanine, a clinically studied and super premium form of L-Theanine that helps to temporarily promote relaxation for your pup.
Delicious Flavour Dogs Love - Your dog will love the tasty turkey flavour while getting pawsome calming support from Chamomile, Valerian Root, Hemp Seed Powder, and L-Tryptophan.
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9.8

Exceptional

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03
CANNANDA

CB2 Hemp Oil for Dogs [225,000mg / 240mL / Organic] - Natural Hip and Joint Supplement for Dogs - Calming Anxiety Relief - Extra Strength for Pain, Inflammation, Arthritis, Stress, Aggression

8.9 worth the money

8.9 Comfort

8.7 pain management
Main highlights

🇨🇦 MADE IN CANADA 🇨🇦: CB2 is a Canadian brand. All our CB2 products are made in Canada from Canadian grown organic hemp. Join over 1 Million happy, healthy dogs across North America who trust CB2. Click “Add to Cart” or “Subscribe and Save” for great savings. YOUR BEST BUDDY DESERVES THE POWER OF CB2!
VETERINARIAN RECOMMENDED: 100X the strength and effectiveness vs standard hemp oil or glucosamine. Supercharged with 1800mg of proprietary CB2 extract for maximum potency. Doctor formulated and recommended by vets across Canada. Powerful daily support for your dog’s comfort, energy, mobility, and overall wellness
QUALITY ASSURANCE CERTIFIED: Therapeutic Grade + Human Grade. Made with all natural ingredients and certified organic hemp oil rich in Omega 3. Non-GMO. Zero THC. No psychoactive effects. No drowsiness. No sedation. No known side effects. Appropriate for all dogs, all breeds, all sizes, and all ages. Registered with Health Canada as a VHP certified dog supplement.
PAIN & INFLAMMATION: Is your best friend slowing down because of joint pain or arthritis? Don’t let pain steal your dog’s best years. CB2 is the most effective hip and joint supplement for dogs, delivering powerful support for pain, stiffness, inflammation, and mobility issues. Excellent for arthritis, joint pain, hip dysplasia, aging, and injuries. Helps bring back comfort, flexibility, strength, and quality of life. Excellent for senior dogs and ideal for all ages
EXTRA LARGE 240mL BOTTLE: Bigger bottle. Better value. While many companies sell tiny 30mL or 60mL bottles, our extra large 240mL bottle gives you far more oil for long-term daily use. Outstanding value for dogs who need consistent daily support. More effective than glucosamine for dogs, fish oil for dogs, omega 3 for dogs, and salmon oil for dogs
ANXIETY & STRESS: It’s heartbreaking to watch your dog suffer from fear, anxiety, and stress. CB2 helps bring your dog back to a calm, relaxed, and emotionally balanced state. Powerful calming relief for dogs without sedation. Excellent for separation anxiety, travel, grooming, motion sickness, and tension caused by changes in your dog’s daily routine. Helps reduce aggression, excessive barking, hyperactivity, and nervous behavior
100% GUARANTEED: We are so confident in the premium quality of our CB2 products that we promise a full money-back guarantee on your FIRST bottle! If you are not 100% satisfied with your first bottle for any reason, we will issue you an immediate refund. No questions asked. No return required. Try it absolutely risk-free! We truly care about your dogs, and we value integrity and trust. IMPORTANT: Amazon does not allow returns of pet health products. To activate your satisfaction guarantee, follow the instructions and customer service contact provided on the paper insert included with every bottle
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9.7

Exceptional

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04
Bark&Spark

Calming Hemp Treats for Dogs - Made in USA with Hemp Oil - Anxiety Relief - Separation Aid - Stress Relief During Fireworks, Storms, Thunder - Aggressive Behavior, Barking - 120 Soft Chews

8.0 Taste

8.0 worth the money

8.0 pain management
Main highlights

Natural Formula for All Breeds and Sizes - product formulated with known effective calming ingredients, like hemp oil, chamomile and passion flower extracts, this treats are effective but more importantly safe and healthy supplement. No chemical relaxants or sedatives are used in this formula. Suitable for hyper dogs of all breeds and sizes.
Moderate Aggressive or Hyperactive Behavior - dog's aggressive behaviour like barking or growling, or hyperactive stolling or running is often caused by unfamiliar surrounding or stressful activity (like a visit to a veterinarian or car ride), and our calming treats can be used to keep your 4 paws friend calm and composed even in the most stressful moments.
Made in USA from Sustainably Sourced Ingredients - these calming hemp bites are made in the USA, with USA grown and processed ingredient. Treats contain absolutely NO sugar, dairy or cord.
Effective Calming Supplement - these calming treats help reduce symptoms of anxiety or stress such as growling, barking, scratching, chewing, licking, uncontrolled urination etc. Anti-anxiety treats are specially formulated to calm down your pet's anxiety, aggression during separation, car rides, thunders, firework etc
A Treat with Delicious Flavor - even the best supplement won't be any good if the dog won't eat it, so we added natural bacon flavoring to our products, so even a picky eater will love it.
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9.6

Exceptional

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05
Bark&Spark

Advanced Calming Hemp Treats for Dogs - Hemp Oil + Melatonin - Anxiety Relief - Separation Aid - Stress Relief During Fireworks, Storms, Thunder - Aggressive Behavior, Barking - 120 Soft Chews

9.1 Aroma

9.1 Taste

8.7 worth the money
Main highlights

Moderate Anxiety and Stress - these calming treats help reduce symptoms of anxiety or stress such as growling, barking, scratching, chewing, licking, uncontrolled urination etc. Anti-anxiety treats can be used to relax your pet during separation, car rides, vet visits, thunders, firework etc
Moderate Aggressive or Hyperactive Behavior - dog's aggressive behaviour like barking or growling, or hyperactive strolling or running is often caused by unfamiliar surrounding or stressful events, so our calming treats are formulated to keep your buddy calm and composed even in the most stressful moments.
Is Your Dog a Picky Eater? We stick to simple formulas rich in natural bacon flavor, that could tempt a fussy eater. No hassle with pills, powder, tablets or capsules
Bark&Spark Commitment - we are keen to give best treatment to our furry customers and we take no compromise when it comes to product quality. Our calming treats are made in the USA, with human grade ingredients
Advanced Dog Calming with Melatonin - formulated with known effective calming ingredients, like hemp oil, valerian root, chamomile and melatonin, this treats are effective but more importantly safe and healthy supplements. No chemical relaxants or sedatives are used. Suitable for hyper dogs of all breeds, sizes. Safe to use for puppies as well.
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9.5

Excellent

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06
Rescue Remedy

Bach RESCUE PET Dropper 10mL, For Dogs, Cats, and Pet Horses, Natural Flower Essence, Thunder, Fireworks and Travel

19% Off
Main highlights

TRUSTED BY PET LOVERS WORLDWIDE: Made with the original RESCUE REMEDY tincture - Dr. Bach's blend of 5 natural flower essences, hand-picked from his original gardens in the UK
FOR DOGS, CATS & PET HORSES: Ideal for pet situations like visiting the veterinarian or groomer, thunder storms, fireworks, separation and travel
EASY TO USE: Administer orally on a full stomach. Add 4 drops into your pet’s food, water bowl, or on a treat. Repeat as needed. Can be used with other wellness products including anxiety medications and thunder calming shirts
DOCTOR DEVELOPED FORMULA: Plant-based natural active ingredients, vegan, vegetarian. Pet-friendly non-alcohol formula
BACH RESCUE PET DROPPER: A pet-safe RESCUE REMEDY formula to help support pets' emotional balance and healthy behaviour
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9.4

Excellent

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07
CANNANDA

CB2 Hemp Oil for Dogs [100 ML/Organic] Hip and Joint Supplement for Dogs - Extra Strength for Pain & Anxiety. Relieves Pain/Arthritis/Inflammation/Separation Anxiety/Stress/Made in Canada

8.9 worth the money

8.9 Comfort

8.7 pain management
Main highlights

🇨🇦 MADE IN CANADA 🇨🇦: CB2 is a Canadian brand. All our CB2 products are made in Canada from Canadian ingredients. Join over 1 Million happy, healthy dogs across North America who trust CB2. Click “Add to Cart” or “Subscribe & Save” for super savings. YOUR BEST BUDDY DESERVES THE ULTRA-CONCENTRATED POWER OF CB2!
VETERINARIAN RECOMMENDED: 100X the strength and effectiveness vs regular hemp oil. Contains a powerful 225,000mg of organic hemp oil + Omega 3 + CB2 extract for maximum potency. CAUTION: most companies sell tiny 30mL or 60mL bottles. Our larger 100mL bottle delivers excellent value and long-term benefits for your dog
STRONGER AND MORE EFFECTIVE THAN: fish oil for dogs / salmon oil for dogs / omega 3 for dogs / hemp treats / glucosamine for dogs. Unleash the power of CB2 for your dog's health and wellness. EXCELLENT RESULTS: Join over 1 Million happy and healthy dogs across North America who trust CB2!
QUALITY ASSURANCE CERTIFIED: Therapeutic Grade + Human Grade. Made with all natural, pure ingredients and certified organic hemp oil from Canadian-grown hemp. Non-GMO. Zero THC. No psychoactive effects. No drowsiness. No sedation. No known side effects. Appropriate for dogs of all breeds, sizes, and ages. Registered with Health Canada as a certified Veterinary Health Product (VHP). Made in Canada by a Canadian company
PAIN & INFLAMMATION: Is your best friend slowing down because of joint pain or arthritis? Don’t let them suffer any longer. CB2 Hip and Joint Supplement For Dogs is rich in Omega 3 and highly effective for pain, stiffness, and mobility issues. Excellent for arthritis, joint pain, hip dysplasia, aging, and injuries. Helps support joint lubrication, mobility, and flexibility. Stronger than glucosamine for dogs. Excellent for senior dogs and ideal for all breeds and ages
ANXIETY & STRESS: It's so hard to watch our best friends suffer from fear, anxiety, and stress. CB2 helps your dog maintain a calm and relaxed nature without sedation. Helps with separation anxiety, travel, motion sickness, and tension caused by changes in your dog’s daily routine. Significantly lowers stress levels and also helps reduce behavioral issues such as aggression, excessive barking, and hyperactivity
100% GUARANTEED: We are so confident in the premium quality of our CB2 products that we promise a full money-back guarantee on your FIRST bottle! If you are not 100% satisfied with your first bottle for any reason, we will issue you an immediate refund. No questions asked. No return required. Try it absolutely risk-free! We truly care about your dogs, and we value integrity and trust. IMPORTANT: Amazon does not allow returns of pet health products. To activate your satisfaction guarantee, follow the instructions and customer service contact provided on the paper insert included with every bottle
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9.2

Excellent

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08
healthybud

Healthybud Duck Calming Soft Chews for Dogs – Grain-Free Dog Treats for Anxiety, Separation & Travel Support – Soft & Chewy High-Value Rewards – Made in Canada – 130 g (4.6 oz)
Main highlights

SOFT & EASY TO PORTION - Moist, soft chews that are gentle on teeth and easy to break apart for small dogs, puppies, adult dogs, and seniors. Serve whole, halve for training rewards, crumble over meals as a topper, or use in treat-dispensing cameras.
REAL DUCK HIGH-VALUE TREATS - Made with real duck and duck liver for a rich aroma and soft, chewy texture that dogs crave. Ideal for picky eaters, positive reinforcement training, or dogs who turn down harder biscuits.
MADE IN CANADA - Produced in Canada using thoughtfully selected ingredients and packaged in a resealable pouch for freshness, quality, and convenience.
GRAIN-FREE CALMING DOG TREATS - Grain-free duck soft chews made without artificial fillers or preservatives. Suitable for all breeds and life stages. Intended for supplemental feeding only.
FORMULATED FOR CALM ROUTINES - Crafted with ingredients commonly included in calming-focused dog recipes to support relaxed behavior and balanced temperament. Designed for use before car rides, fireworks, thunderstorms, grooming, vet visits, nail trims, training sessions, or other stimulating moments as part of your dog’s daily routine.
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8.9

Very Good

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09
Vetoquinol

Vetoquinol Zylkene – Veterinary Health Product - Calm and Relaxed Behaviour in Pets During Stressful Events - 75 mg - Cats and Small Dogs - 30 Caps
Main highlights

GREAT TASTE YOUR PET WILL LOVE: Loved by pets and owners with real–world evidence.
EASY TO ADMINISTER CAPSULES FOR CATS AND DOGS: May be given directly to the pet or the capsule can be opened, and the powder mixed in its food.
EASE OF ADMINISTRATION: With a proven palatability.
CALMS PETS DURING STRESSFUL EVENTS: With a favourable safety profile.
ACTIVE INGREDIENTS OF NATURAL ORIGIN: Contains Alpha–casozepine, a peptide derived from milk.
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8.8

Very Good

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10
STRELLALAB

Hemp Calming Chews for Dogs - Dog Calming Treats - Anxiety Relief Treats - Dog Calming Chews - Stress - Sleep Calming Aid - Health & Wellness Supplements for Dog Separation Barking - 120 Treats
Main highlights

Zero Side Effects: This anti anxiety dog treatment contains 120 soft chews, made with premium quality, all-natural and safe ingredients. No chemical relaxants or sedatives are used. Easy to serve treats, no hassle with pills, capsules or powder.
One Chew to Calm Them All - whether your best friend is small yorkie or large retriever, these chewable treats would be effective to the maximum, providing an extra bit of composure and calmness during stressful events like fireworks, thunderstorms, travel, car rides, vet visits etc.
Moderate Aggressive and Hyperactive Behavior - chewies advanced formula takes advantage of herb extracts and oils to chill stressed dogs, relax hyper active ones and reduce aggression.
Mild Formula - hemp dog treats for calming and sleep aid come with natural bacon flavoring making sure your canine friend will love them. Suitable for adult dogs and puppies of all breeds. *Please, refer to the serving chart to adjust a daily dose.
Effective Stress and Anxiety Relief - hemp chews for dogs are created to ease anxious behavior such as growling, barking, scratching, chewing, licking, uncontrolled urination etc.
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8.6

Very Good

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